US2018042467A1PendingUtilityA1

Devices for continual monitoring and introduction of gastrointestinal microbes

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Assignee: GEARBOX LLCPriority: Jun 29, 2009Filed: Oct 26, 2017Published: Feb 15, 2018
Est. expiryJun 29, 2029(~3 yrs left)· nominal 20-yr term from priority
Inventors:Mahalaxmi Gita BangeraEdward S. BoydenRoderick A. HydeJordin T. KareEric C. LeuthardtDennis J. RivetLowell L. Wood, Jr.
A61B 5/0002G06F 19/12A61B 5/411A61B 5/42A61B 1/041G06F 19/366G06F 19/18G16B 20/20G16B 5/00Y02A90/10G16B 20/00G16H 10/40
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Claims

Abstract

Systems and methods described herein include those for the continual modification of intestinal microbes. Described herein are systems including sampling devices, analysis devices, computational devices and user interface devices as well as methods for the use of such devices in combination.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 .- 48 . (canceled) 
     
     
         49 . A system for monitoring and introducing gastrointestinal microbes into a mammalian gastrointestinal tract over time, comprising:
 two or more sampling devices;   one or more analysis device;   at least one computational device configured to receive information from the one or more analysis device;   at least one user interface operably connected to the at least one computational device; and   at least one dispenser operably connected to the at least one computational device.   
     
     
         50 . The system of  claim 49 , wherein the two or more sampling devices comprise:
 one or more dietary sampling devices.   
     
     
         51 . The system of  claim 49 , wherein the two or more sampling devices comprise:
 two or more passive sampling devices.   
     
     
         52 . The system of  claim 49 , wherein the two or more sampling devices comprise:
 one or more additional devices configured to yield additional information about a sample collection.   
     
     
         53 . The system of  claim 49 , wherein the two or more sampling devices comprise:
 an antenna.   
     
     
         54 . The system of  claim 49 , wherein the two or more sampling devices comprise:
 one or more electronic detector.   
     
     
         55 . The system of  claim 49 , wherein the one or more analysis device is configured to come in direct contact with each of the two or more sampling devices for analysis of a sample. 
     
     
         56 . The system of  claim 49 , wherein the one or more analysis device is configured for nucleic acid analysis of the microbes present in a sample. 
     
     
         57 . The system of  claim 49 , wherein the one or more analysis device and the at least one computational device are integrated into a single unit. 
     
     
         58 . The system of  claim 49 , wherein the at least one computational device is configured to accept data regarding an analysis of at least one sample and compare the accepted data to a standard profile. 
     
     
         59 . The system of  claim 49 , wherein the at least one dispenser is configured to dispense at least one microbe, antibiotic, antifungal, prebiotic agent, probiotic agent, or nutritional supplement. 
     
     
         60 . The system of  claim 49 , wherein the at least one dispenser comprises:
 an antenna.   
     
     
         61 . The system of  claim 49 , wherein the at least one dispenser comprises:
 a database of potential agents possible to dispense.   
     
     
         62 . The system of  claim 49 , wherein the at least one dispenser comprises:
 a database of codes to signal or indicate when a specific dispensation protocol should be initiated.   
     
     
         63 . A system for monitoring and introducing gastrointestinal microbes into a mammalian gastrointestinal tract over time, comprising:
 two or more sampling devices;   one or more analysis device;   at least one computational device configured to receive information from the one or more analysis device and configured to signal a dispensing device information relating to time, quantity, location or identity of material to dispense; and   at least one dispenser operably connected to the at least one computational device, the at least one dispenser configured to receive information relating to time, quantity, location or identity of material to dispense from the at least one computational device.   
     
     
         64 . The system of  claim 63 , wherein the two or more sampling devices comprise:
 one or more dietary sampling devices.   
     
     
         65 . The system of  claim 63 , wherein the two or more sampling devices comprise:
 two or more passive sampling devices.   
     
     
         66 . The system of  claim 63 , wherein the two or more sampling devices comprise:
 one or more additional devices configured to yield additional information about a sample collection.   
     
     
         67 . The system of  claim 63 , wherein the two or more sampling devices comprise:
 an antenna.   
     
     
         68 . The system of  claim 63 , wherein the two or more sampling devices comprise:
 one or more electronic detector.   
     
     
         69 . The system of  claim 63 , wherein the one or more analysis device is configured to come in direct contact with each of the two or more sampling devices for analysis of a sample. 
     
     
         70 . The system of  claim 63 , wherein the one or more analysis device is configured for nucleic acid analysis of the microbes present in a sample. 
     
     
         71 . The system of  claim 63 , wherein the one or more analysis device and the at least one computational device are integrated into a single unit. 
     
     
         72 . The system of  claim 63 , wherein the at least one computational device is configured to accept data regarding an analysis of at least one sample and compare the accepted data to a standard profile. 
     
     
         73 . The system of  claim 63 , wherein the at least one dispenser is configured to dispense at least one microbe, antibiotic, antifungal, prebiotic agent, probiotic agent, or nutritional supplement. 
     
     
         74 . The system of  claim 63 , wherein the at least one dispenser comprises:
 an antenna.   
     
     
         75 . The system of  claim 63 , wherein the at least one dispenser comprises:
 a database of potential agents possible to dispense.   
     
     
         76 . The system of  claim 63 , wherein the at least one dispenser comprises:
 a database of codes to signal or indicate when a specific dispensation protocol should be initiated.   
     
     
         77 . A system for monitoring and introducing gastrointestinal microbes into a mammalian gastrointestinal tract, comprising:
 at least one gastrointestinal microbe analysis device;   at least one computational device;   at least one user interface operably connected to the at least one computational device; and   at least one dispenser operably connected to the at least one computational device.   
     
     
         78 . The system of  claim 77 , wherein the at least one gastrointestinal microbe analysis device comprises:
 a dietary sampling device.   
     
     
         79 . The system of  claim 77 , wherein the at least one gastrointestinal microbe analysis device comprises:
 a passive sampling device.   
     
     
         80 . The system of  claim 77 , wherein the at least one gastrointestinal microbe analysis device comprises:
 one or more additional devices configured to yield additional information about a sample collection.   
     
     
         81 . The system of  claim 77 , wherein the at least one gastrointestinal microbe analysis device comprises:
 an antenna.   
     
     
         82 . The system of  claim 77 , wherein the at least one gastrointestinal microbe analysis device comprises:
 one or more electronic detector.   
     
     
         83 . The system of  claim 77 , wherein the at least one gastrointestinal microbe analysis device is configured for nucleic acid analysis of the microbes present in a sample. 
     
     
         84 . The system of  claim 77 , wherein the at least one gastrointestinal microbe analysis device and the at least one computational device are integrated into a single unit. 
     
     
         85 . The system of  claim 77 , wherein the at least one computational device is configured to accept data regarding an analysis of at least one sample and compare the accepted data to a standard profile. 
     
     
         86 . The system of  claim 77 , wherein the at least one dispenser is configured to dispense at least one microbe, antibiotic, antifungal, prebiotic agent, probiotic agent, or nutritional supplement. 
     
     
         87 . The system of  claim 77 , wherein the at least one dispenser comprises:
 an antenna.   
     
     
         88 . The system of  claim 77 , wherein the at least one dispenser comprises:
 a database of potential agents possible to dispense.   
     
     
         89 . The system of  claim 77 , wherein the at least one dispenser comprises:
 a database of codes to signal or indicate when a specific dispensation protocol should be initiated.

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