US2018044367A1PendingUtilityA1
Nucleoside phosphoramidates
Est. expiryMay 20, 2029(~2.9 yrs left)· nominal 20-yr term from priority
Inventors:Byoung-Kwon ChunGanapati Reddy PamulapatiSuguna RachakondaBruce RossMichael Joseph SofiaPeiyuan WangHai-Ren Zhang
A61K 45/00A61K 31/716C07F 9/65586A61P 31/12C07H 19/10A61K 31/7072A61P 31/00A61P 1/16C07F 9/242Y02P20/55A61P 31/14C07F 9/24A61K 31/67A61P 3/12C07H 1/00A61K 31/675C07H 17/02A61P 31/16A61K 31/664Y02A50/30
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Abstract
Disclosed herein are nucleoside phosphoramidates and their use as agents for treating viral diseases. These compounds are inhibitors of RNA-dependent 5 RNA viral replication and are useful as inhibitors of HCV NS5B polymerase, as inhibitors of HCV replication and for treatment of hepatitis C infection in mammals.
Claims
exact text as granted — not AI-modified1 .- 81 . (canceled)
82 . A compound of formula:
wherein Z is —C(O)(CH 2 ) 2 C(O)CH 3, —Si(CH 3 ) 2 t Bu or —Si(i—Pr) 2 -O—Si(i—Pr) 2 -OH.Cited by (0)
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