Partially buffered free acid and/or ketone blend for rapid onset ketosis and metabolic therapy

Abstract

A foodstuff can include a free acid β-hydroxybutyrate, and a base. The β-hydroxybutyrate, and base, are present at a less than 1:1 molar equivalence. Ketone Ester may also be incorporated as a component of the foodstuff.

We claim: 
     
         1 . A foodstuff comprising:
 free acid β-hydroxybutyrate; and   a base.   
       wherein the base is less than a 1:1 molar equivalent with respect to the free acid β-hydroxybutyrate. 
     
     
         2 . The foodstuff of  claim 1 , having a molar ratio 10 parts free acid β-hydroxybutyrate and between 2-8 parts of the base. 
     
     
         3 . The foodstuff of  claim 1 , wherein the free acid β-hydroxybutyrate is replaced with an enantiomerically enriched (D)-β-hydroxybutyrate. 
     
     
         4 . The foodstuff of  claim 1 , wherein the free acid β-hydroxybutyrate is replaced with an enantiomerically pure (D)-β-hydroxybutyrate. 
     
     
         5 . The foodstuff of  claim 1 , further comprising a Ketone Ester. 
     
     
         6 . The foodstuff of  claim 1 , wherein the foodstuff is encapsulated with an enteric coating. 
     
     
         7 . The foodstuff of  claim 1 , wherein the foodstuff is administered with a stomach acid inhibitor. 
     
     
         8 . The foodstuff of  claim 1 , wherein the base is comprised of at least one of the following; Na+, K+, and Ca+. 
     
     
         9 . A method of consuming a foodstuff to elevate ketone levels in the body of a user comprising the steps of:
 consuming a free acid β-hydroxybutyrate and a base at an effective dose,   wherein the amount of base is less than a 1:1 molar equivalent with respect to the free acid β-hydroxybutyrate.   
     
     
         10 . The method of  claim 9 , wherein a Ketone Ester is consumed. 
     
     
         11 . The method of  claim 9 , wherein the effective dose is defined as up to 2 g/kg of body weight per day, wherein the effective dose treats erectile dysfunction. 
     
     
         12 . The method of  claim 9 , wherein the effective dose is defined as up to 2 g/kg of body weight per day, wherein the effective dose treats hair loss. 
     
     
         13 . The method of  claim 9 , wherein the effective dose is defined as up to 2 g/kg of body weight per day, wherein the effective dose improves visual acuity. 
     
     
         14 . The method of  claim 9 , wherein the effective dose is defined as up to 2 g/kg of body weight per day, wherein the effective dose treats amyotrophic lateral sclerosis. 
     
     
         15 . The method of  claim 9 , wherein the effective dose is defined as up to 2 g/kg of body weight per day, wherein the effective dose treats a brain injury. 
     
     
         16 . The method of  claim 9 , wherein the effective dose is defined as up to 2 g/kg of body weight per day, wherein the effective dose enhances athletic performance. 
     
     
         17 . The method of  claim 16 , wherein 0.5 to 2 times the amount of carbohydrates with respect to the effective dose are consumed by the user. 
     
     
         18 . The method of  claim 17 , wherein the carbohydrates are administered prior to the ketones. 
     
     
         19 . The method of  claim 9 , wherein the effective dose is defined as up to 2 g/kg of body weight per day, wherein the effective dose prevents hyperglycemia. 
     
     
         20 . The method of  claim 9 , wherein the effective dose is defined as up to 2 g/kg of body weight per day, wherein the effective dose improves myocardial blood flow and efficiency.