Temperature compensation for an analyte measurement determined from a specified sampling time derived from a sensed physical characteristic of the sample containing the analyte

Abstract

Various embodiments for a method, systems and meters that allow for a more accurate analyte concentration with a biosensor by determining at least one physical characteristic of the sample and compensating for the effects of ambient temperature with a defined relationship between temperature in the environment, the meter or the biosensor.

1 . A method of adjusting for the effect of temperature upon a biosensor having a plurality of electrodes with at least two electrodes provided with enzymes thereon, the method comprising the steps of:
 applying a signal to the at least two electrodes;   initiating an electrochemical reaction between the at least two electrodes and an analyte in a fluid sample to cause a transformation of the analyte into a byproduct;   measuring a signal output from the at least two electrodes during the electrochemical reaction;   measuring a temperature proximate the biosensor;   calculating an analyte value representative of a quantity of analyte in the fluid sample from the signal output;   adjusting the analyte value to a final analyte value by a temperature compensation term defined by a relationship where:
 (a) the temperature compensation term increases for increasing analyte values; and 
 (b) the temperature compensation term is inversely related to the biosensor temperature in a range of about 5 degrees Celsius to about 22 degrees Celsius; 
 (c) the temperature compensation term is about zero for the ambient temperature proximate the biosensor from about 22 degrees Celsius to about 45 degrees Celsius; 
   and   annunciating the final value representative of the quantity of analyte in the fluid sample.