System of injectable fully-monolithic wireless bio-sensing

Abstract

Systems are provided for a wireless system-on-chip (SoC) with integrated antenna, power harvesting, and biosensors. An illustrative SoC can have a dimension of 200 μm×200 μm×100 μm to allow painless injection. Such small device size is enabled by: a 13 μm×20 μm 1 nA current reference, optical clock recovery, low voltage inverting dc-dc to enable use of higher quantum efficiency diodes, on-chip resonant antenna, and an array-scanning reader.

What is claimed is: 
     
         1 . A system-on-chip (SoC) sensing system, the system comprising:
 a measurement reader having at least one reader antenna for transmitting a signal to a SoC, the measurement reader being not located on the SoC; and   the SoC comprising:
 a receiving antenna for receiving the signal transmitted from the at least one reader antenna; 
 a power supply subsystem powered by the signal received by the receiving antenna, the power supply subsystem comprising a plurality of diodes; 
 a clock recovery subsystem powered by the signal received by the receiving antenna, the clock recovery system comprising a set of diodes; and 
 a sensor subsystem, the sensor subsystem generating a digital signal for modulating the signal transmitted by the measurement reader 
   
     
     
         2 . The system of  claim 1 , wherein the sensor subsystem includes an electrochemical sensor. 
     
     
         3 . The system of  claim 1 , wherein the sensor subsystem includes a light sensor. 
     
     
         4 . The system of  claim 1 , wherein the sensor subsystem includes a capacitance sensor. 
     
     
         5 . The system of  claim 1 , wherein the SoC has a dimension equal to or less than 200 μm×200 μm×100 μm. 
     
     
         6 . The system of  claim 1 , wherein the SoC is injected into a skin at a depth ranging from about 1 mm to about 4 mm. 
     
     
         7 . The system of  claim 1 , wherein the power supply include a charge pump. 
     
     
         8 . The system of  claim 1 , wherein the SoC further comprising a current reference having a switched capacitor reference. 
     
     
         9 . The system of  claim 1 , wherein the SoC further comprising a DC-to-DC low voltage converter. 
     
     
         10 . The system of  claim 1 , wherein the signal transmitted by the measurement reader is an optical signal in a range of radio frequency.