Fold-Up Containment Device For Bone Defects

Abstract

A bone graft system includes a two-dimensional mesh sheet sized and shaped to, when folded along fold lines, form a three-dimensional graft containment structure configured to be packed with a bone graft material for placement within a target area of a bone, the mesh sheet including a first end flap connected to a remaining portion of the mesh sheet via a first fold line and a second end flap connected to the remaining portion of the mesh sheet via a second fold line, a third fold line extending from the first fold line to the second fold line so that the remaining portion is configured to be wrapped around folded first and second end flaps to form the graft containment structure, the first and second end flaps substantially corresponding to a profile of the target area of the bone.

What is claimed is: 
     
         1 . A bone graft system, comprising:
 a two-dimensional mesh sheet sized and shaped to, when folded along fold lines, form a three-dimensional graft containment structure configured to be packed with a bone graft material for placement within a target area of a bone, the mesh sheet including a first end flap connected to a remaining portion of the mesh sheet via a first fold line and a second end flap connected to the remaining portion of the mesh sheet via a second fold line, a third fold line extending from the first fold line to the second fold line so that the remaining portion is configured to be wrapped around folded first and second end flaps to form the graft containment structure, the first and second end flaps substantially corresponding to a profile of the target area of the bone.   
     
     
         2 . The system of  claim 1 , wherein the mesh sheet comprises an overlapping portion connected to the remaining portion of the mesh sheet via a fourth fold line. 
     
     
         3 . The system of  claim 1 , wherein, when the mesh sheet is folded to form the three-dimensional graft containment structure, one of a first end and a second end of the graft containment structure include an overhang extending beyond one of the folded first and second end flaps. 
     
     
         4 . The system of  claim 3 , the overhang configured to extend over a portion of bone to fix the graft containment structure thereto. 
     
     
         5 . The system of  claim 4 , the overhang including an opening extending therethrough, the opening sized and shaped for receiving a bone fixation element therethrough. 
     
     
         6 . The system of  claim 1 , wherein the mesh sheet is formed via a plurality of pores extending therethrough. 
     
     
         7 . The system of  claim 6 , wherein the mesh sheet is formed via a plurality of intersecting struts, the intersecting struts defining the plurality of pores. 
     
     
         8 . The system of  claim 1 , wherein first and second longitudinal edges of the mesh sheet extend along a curve and include intersecting longitudinal fold lines and lateral fold lines. 
     
     
         9 . The system of  claim 8 , wherein a portion of the lateral fold lines include a slit extending therealong so that, when folded, the bone graft containment structure extends along a curve corresponding to a curvature of a patient's mandible. 
     
     
         10 . A bone graft system, comprising:
 a graft containment assembly including a plurality of two-dimensional mesh sheets connected to one another along longitudinal edges thereof, each of the mesh sheets sized and shaped so that, when folded along fold lines, each of the mesh sheets form a three-dimensional graft containment structure configured to be packed with a bone graft material, each graft containment structure movable relative to an adjacent graft containment structure to form a desired configuration of the graft containment assembly for placement of the graft containment assembly within a target area of a bone.   
     
     
         11 . The system of  claim 10 , wherein each of the mesh sheets includes a first end flap connected to a remaining portion of the mesh sheet via a first fold line and a second end flap connected to the remaining portion of the mesh sheet via a second fold line, a third fold line extending from the first fold line to the second fold line so that the remaining portion is configured to be wrapped around folded first and second end flaps to form the graft containment structure, the first and second end flaps substantially corresponding to a profile of the target area of the bone. 
     
     
         12 . The system of  claim 10 , wherein a size and shape of each of the mesh sheets may vary so that a cross-sectional area of the graft containment structures may vary along a length of the graft containment assembly. 
     
     
         13 . The system of  claim 10 , wherein one of a first mesh sheet at a first end of the graft containment assembly and a second mesh sheet at a second end of the graft containment assembly includes an overhang so that, when the graft containment assembly is positioned within the target area, the overhang extends over a portion of the bone. 
     
     
         14 . The system of  claim 10 , further comprising a bone plate configured to be positioned over a length of the graft containment assembly to fix adjacent bone graft containment structured relative to one another. 
     
     
         15 . The system of  claim 14 , wherein, when the mesh sheets are folded to form graft containment structures, each of the graft containment structures include a groove extending therein, the groove sized and shaped to receive the bone plate. 
     
     
         16 . A method for treating a bone, comprising:
 folding a first two-dimensional mesh sheet along fold lines to form a first three-dimensional graft containment structure, the first mesh sheet including a first end flap connected to a remaining portion of the mesh sheet via a first fold line and a second end flap connected to the remaining portion of the mesh sheet via a second fold line, a third fold line extending from the first fold line to the second fold line so that the remaining portion is configured to be wrapped around folded first and second end flaps to form the first graft containment structure;   packing the first graft containment structure with a bone graft material;   maintaining the first graft containment structure in a closed configuration, so that the bone graft material is held therewithin;   positioning the first graft containment structure within a target area of a bone; and   fixing the first graft containment structure to the bone.   
     
     
         17 . The method of  claim 16 , wherein maintaining the first graft containment structure in the closed configuration includes one of suturing and hooking longitudinal edges of the first graft containment structure together. 
     
     
         18 . The method of  claim 16 , further comprising folding a second two-dimensional mesh sheet along fold lines to form a second three-dimensional graft containment structure, the second mesh sheet including a first end flap connected to a remaining portion of the mesh sheet via a first fold line and a second end flap connected to the remaining portion of the mesh sheet via a second fold line, a third fold line extending from the first fold line to the second fold line so that the remaining portion is configured to be wrapped around folded first and second end flaps to form the second graft containment structure, the first and second mesh sheets connected to one another along longitudinal edges thereof so that the first and second graft containment structures are movable relative to one another. 
     
     
         19 . The method of  claim 18 , further comprising attaching a bone plate to each of the first and second graft containment structures and to a portion of bone over which an end of the bone plate extends. 
     
     
         20 . The method of  claim 16 , further comprising fixing the first graft containment structure to the bone by inserting a bone fixation element through an overhang extending from the first graft containment structure to extend over a portion of bone. 
     
     
         21 . The method of  claim 16 , wherein the first two-dimensional mesh sheet is designed using a virtual three-dimensional shape based on a patient's specific bone dimensions. 
     
     
         22 . The method of  claim 21 , wherein the patient's specific bone dimensions are obtained from a 3D image of the patient's bone.