US2018127447A1PendingUtilityA1

Metathesis catalysts and methods thereof

Assignee: TRUSTEES BOSTON COLLEGEPriority: Nov 5, 2014Filed: Nov 17, 2017Published: May 10, 2018
Est. expiryNov 5, 2034(~8.3 yrs left)· nominal 20-yr term from priority
B01J 2531/66C07C 17/275B01J 31/2265C07F 11/00C07D 333/54C07C 21/14C07J 51/00C07F 5/025C07C 41/30C07D 209/10C07J 9/00C07C 45/63C07C 17/14C07B 37/04B01J 2231/543C07C 37/62B01J 2531/64C07C 17/269C07C 67/333C07D 209/48C07C 2601/14C07C 2603/26C07C 17/266C07C 22/08C07C 67/307C07C 17/278C07C 17/361C07C 17/10C07C 17/02C07F 7/1804C07C 69/753C07C 21/18C07C 21/19C07C 43/225C07C 25/24C07C 21/04C07F 7/1852C07C 22/04C07C 69/63C07C 43/192C07C 43/17C07C 69/65C07C 25/28C07F 7/1844
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Claims

Abstract

The present application provides, among other things, compounds and methods for metathesis reactions. In some embodiments, the present disclosure provides methods for preparing alkenyl halide with regioselectivity and/or stereoselectivity. In some embodiments, the present disclosure provides methods for preparing alkenyl halide with regioselectivity and Z-selectivity. In some embodiments, the present disclosure provides methods for preparing alkenyl halide with regioselectivity and E-selectivity. In some embodiments, provided technologies are particularly useful for preparing alkenyl fluorides. In some embodiments, a provided compound useful for metathesis reactions has the structure of formula II-a. In some embodiments, a provided compound useful for metathesis reactions has the structure of formula II-b.

Claims

exact text as granted — not AI-modified
1 - 20 . (canceled) 
     
     
         21 . A compound of formula 
       
         
           
           
               
               
           
         
         wherein 
         M is Mo or W; 
         R 1  is 
       
       
         
           
           
               
               
           
         
         one of R 2  and R 3  is hydrogen, and the other is optionally substituted C 1-6  aliphatic; 
         R 4  is optionally substituted 
       
       
         
           
           
               
               
           
         
         R 5  is optionally substituted 1-pyrrolyl 
       
       
         
           
           
               
               
           
         
       
     
     
         22 . The compound of  claim 21 , wherein M is Mo. 
     
     
         23 . The compound of  claim 21 , wherein R 4  is selected from 
       
         
           
           
               
               
           
         
         
           
           
               
               
           
         
       
     
     
         24 . The compound of  claim 21 , wherein R s  is 
       
         
           
           
               
               
           
         
       
     
     
         25 . The compound of  claim 21 , wherein the compound is selected from:

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