Intraocular lens materials and components

Abstract

Materials and methods of manufacturing intraocular lenses, including polymeric materials for the intraocular lenses, fluids for intraocular lenses, and adhesives for intraocular lenses. The intraocular lenses can include an optic portion and a peripheral region in fluid communication.

1 . An intraocular lens comprising a polymeric material, the polymeric material comprising:
 butyl acrylate present in the amount from 2% to 20%, trifluoroethyl methacrylate present in the amount from 10% to 35%, and phenylethyl acrylate present in the amount from 50% to 80%.   
     
     
         2 . The intraocular lens of  claim 1 , wherein the refractive index of the polymeric material is between 1.48 and 1.53. 
     
     
         3 . The intraocular lens of  claim 2 , wherein the refractive index of the polymeric material is between 1.50 and 1.53. 
     
     
         4 . The intraocular lens of  claim 1 , wherein the polymeric material defines a fluid channel, the intraocular lens further comprising a silicone oil in the fluid channel. 
     
     
         5 . The intraocular lens of  claim 4 , wherein the silicone oil is index matched with the polymeric material. 
     
     
         6 . The intraocular lens of  claim 4 , wherein the silicone oil has a polydispersity less than 1.2. 
     
     
         7 . A polymeric material for an ophthalmic device, the polymeric material comprising:
 an alkyl acrylate present in the amount from 3% to 20%;   a fluoroacrylate present in the amount from 10% to 35%; and   a phenyl acrylate present in the amount from 50% to 80%.   
     
     
         8 . An accommodating intraocular lens, comprising:
 an optic portion adapted to refract light onto a retina, the optic portion comprising a polymeric material; and   a silicone oil disposed within the optic portion, wherein the silicone oil has a polydispersity index less than about 1.2.   
     
     
         9 . The accommodating intraocular lens of  claim 8  wherein the mean average molecular weight of the silicone oil is between 4500 and 6500. 
     
     
         10 . The accommodating intraocular lens of  claim 8  wherein the viscosity is no more than 2400 cP. 
     
     
         11 . The accommodating intraocular lens of  claim 8 , wherein the silicone oil comprises diphenyl siloxane units. 
     
     
         12 . The accommodating intraocular lens of  claim 8 , wherein the silicone oil is made from a cyclotrisiloxane comprising a ratio of two dimethyl siloxane units to one diphenyl siloxane unit. 
     
     
         13 . The accommodating intraocular lens of  claim 8  wherein the refractive index of the silicone oil is between 1.47 and 1.53, optionally between 1.50 and 1.53. 
     
     
         14 . An adhesive for an accommodating intraocular lens, wherein the adhesive comprises a first component that is the same or has substantially similar properties as the polymeric material of a first body of the accommodating intraocular lens. 
     
     
         15 . The adhesive of  claim 14 , wherein the adhesive comprises a first component that is the same as the polymeric material of the first body of the intraocular lens. 
     
     
         16 . The adhesive of  claim 15  wherein the adhesive comprises a first component that comprises monomers that are present in the polymeric material. 
     
     
         17 . The adhesive of  claim 14 , wherein the adhesive comprises a second primary component that is a reactive acrylic diluent. 
     
     
         18 . The adhesive of  claim 14 , wherein the adhesive comprises a first component that is not the same but is substantially similar to the polymeric material of the first body of the accommodating intraocular lens. 
     
     
         19 . A method of manufacturing an accommodating intraocular lens, comprising:
 curing first and second components of the accommodating intraocular lens;   applying an adhesive between the first and second components, wherein the adhesive comprises a first component that is the same, substantially the same, or has substantially similar properties as at least one of the first and second components, the adhesive further comprising a second primary component that is a reactive acrylic diluent.   
     
     
         20 . A method of manufacturing a polymeric component of an intraocular lens that includes a plurality of monomers, comprising:
 forming pre-polymer of the polymer, the pre-polymer comprising the plurality of monomers; and   curing the pre-polymer to form the polymeric component.   
     
     
         21 . The method of  claim 20  wherein forming the pre-polymer comprises combining a plurality of monomers with a monomer comprising a hydroxy moiety. 
     
     
         22 . The method of  claim 21  further comprising creating a crosslinkable polymer from the pre-polymer, wherein creating the crosslinkable polymer comprises changing the hydroxyl moiety to a methacrylate moiety.