US2018155347A1PendingUtilityA1

Pharmaceutical compositions comprising perillyl alcohol derivatives

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Assignee: NEONC TECH INCPriority: Feb 12, 2015Filed: Jul 11, 2017Published: Jun 7, 2018
Est. expiryFeb 12, 2035(~8.6 yrs left)· nominal 20-yr term from priority
Inventors:Thomas ChenDaniel LevinSatish Puppali
C07D 231/12A61K 31/495C07D 487/04A61P 35/00C07D 493/04C07D 253/075C07D 493/14
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Claims

Abstract

A pharmaceutical composition is provided which includes perillyl alcohol conjugated with a therapeutic agent and further includes and a hydrolyzable acylated aliphatic tail. A method of using the pharmaceutical composition is also provided for treating a condition or disease of a patient, e.g., cancer.

Claims

exact text as granted — not AI-modified
1 - 31 . (canceled) 
     
     
         32 . A rolipram perillyl alcohol (POH) linoleate triple conjugate compound having a structural formula of: 
       
         
           
           
               
               
           
         
       
     
     
         33 . A lamotrigine perillyl alcohol (POH) linoleate triple conjugate compound having a structural formula of: 
       
         
           
           
               
               
           
         
       
     
     
         34 . A pharmaceutical composition comprising the compound of  claim 32 . 
     
     
         35 . A pharmaceutical composition comprising the compound of  claim 33 .

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