US2018177879A1PendingUtilityA1
External preparation for transdermal administration
Est. expiryJun 5, 2035(~8.9 yrs left)· nominal 20-yr term from priority
A61K 38/13A61K 47/10A61P 37/06A61P 17/06A61P 17/00A61K 9/08A61P 17/14A61K 47/14A61P 37/08A61K 38/00A61K 9/0014
35
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Claims
Abstract
The present invention is intended to provide a cyclosporine external preparation that improves transdermal absorption of cyclosporine. The present invention provides an external preparation containing cyclosporine, ethanol, and a fatty acid monoester.
Claims
exact text as granted — not AI-modified1 . An external preparation comprising cyclosporine, ethanol, and a fatty acid monoester.
2 . The external preparation according to claim 1 , wherein the fatty acid monoester is an ester of a monohydric alcohol of 1 to 22 carbon atoms and a monocarboxylic acid of 6 to 22 carbon atoms.
3 . The external preparation according to claim 1 , wherein the fatty acid monoester is isopropyl myristate, isopropyl palmitate, or 2-hexadecyl isostearate.
4 . The external preparation according to claim 1 , which is substantially free of water used as a solubilizer.
5 . The external preparation according to claim 1 , which is a liquid formulation.
6 . The external preparation according to claim 2 , which is substantially free of water used as a solubilizer.
7 . The external preparation according to claim 3 , which is substantially free of water used as a solubilizer.
8 . The external preparation according to claim 2 , which is a liquid formulation.
9 . The external preparation according to claim 3 , which is a liquid formulation.
10 . The external preparation according to claim 4 , which is a liquid formulation.Cited by (0)
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