Method for the quantification of 227ac in 223ra compositions

Abstract

A method for the quantification of 227 Ac in a 223 Ra composition comprising passing the composition through a first solid phase extraction column A, wherein said column comprises a thorium specific resin, passing the eluate of column A through a second solid phase extraction Column B, wherein said column comprises an actinium specific resin and recovering the 227 Ac absorbed onto the resin in column B and determining the amount thereof.

1 - 21 . (canceled) 
     
     
         22 . Apparatus for the quantification of  227 Ac in a  223 Ra composition comprising
 a first solid phase extraction column A, wherein said column A comprises a thorium specific resin, and   a second solid phase extraction column B, wherein said column B comprises an actinium specific resin.   
     
     
         23 . The apparatus of  claim 22 , wherein column A and column B are arranged in series. 
     
     
         24 . The apparatus of  claim 22 , wherein the thorium specific resin comprises a phosphonate extractant. 
     
     
         25 . The apparatus of  claim 24 , wherein the phosphonate extractant is an alkyl phosphonate extractant. 
     
     
         26 . The apparatus of  claim 22 , wherein the thorium specific resin comprises a dialkyl alkyl phosphonate extractant of Formula I: 
       
         
           
           
               
               
           
         
         wherein each of R 1 -R 3  is independently a C 3 -C 8  straight or branched chain alkyl group. 
       
     
     
         27 . The apparatus of  claim 26 , wherein the dialkyl alkyl phosphonate extractant is a dipentyl pentylphosphonate extractant 
     
     
         28 . The apparatus of  claim 22 , wherein the actinium specific resin comprises a tetra-alkyl diglycolamide extractant of Formula II: 
       
         
           
           
               
               
           
         
         wherein R 1 -R 4  are independently C 3 -C 12  straight or branched chain alkyl groups. 
       
     
     
         29 . The apparatus of  claim 28 , wherein the tetra-alkyl diglycolamide extractant is a N,N,N′,N′-tetra-n-octyldiglycolamide (DGA) extractant.