Lactobacillus strain-containing food composite, oral cleaning composite and medical composite for inhibiting oral pathogens

Abstract

A food composite, an oral cleaning composite or a medical composite contain at least one lactobacillus strain able to inhibit oral pathogens. The lactobacillus strain is at least one isolated lactobacillus strain selected from a group including Lactobacillus acidophilus F-1 strain; Lactobacillus salivarius subsp. salicinius AP-32 strain; Lactobacillus reuteri GL-104 strain; Lactobacillus paracasei GL-156 strain; Lactobacillus helveticus RE-78 strain; Lactobacillus rhamnosus CT-53 strain; and Lactobacillus paracasei ET-66 strain. The abovementioned lactobacillus strains are able to inhibit oral pathogens and carried by a food composite, an oral cleaning composite or a medical composite.

What is claimed is: 
     
         1 . A  lactobacillus  strain-containing food composite comprising:
 at least one  lactobacillus  strain able to inhibit oral pathogens, which is at least one isolated  lactobacillus  strain selected from a group including  Lactobacillus acidophilus  F-1 strain, CCTCC NO: M2011124;  Lactobacillus salivarius  subsp.  salicinius  AP-32 strain, CCTCC NO: M2011127;  Lactobacillus reuteri  GL-104 strain, CCTCC NO: M209138;  Lactobacillus paracasei  GL-156 strain, CCTCC NO: M2014590;  Lactobacillus helveticus  RE-78 strain, CGMCC No. 13513;  Lactobacillus rhamnosus  CT-53 strain, CCTCC NO: M2011129; and  Lactobacillus paracasei  ET-66 strain, CGMCC No. 13514, which are respectively preserved in China Center for Type Culture Collection (CCTCC) and China General Microbiological Culture Collection Center (CGMCC); and   an excipient or diluent, which is physiologically acceptable.   
     
     
         2 . The  lactobacillus  strain-containing food composite according to  claim 1 , wherein the  lactobacillus  strain is an active strain. 
     
     
         3 . The  lactobacillus  strain-containing food composite according to  claim 1 , wherein the  lactobacillus  strain is a deactivated strain. 
     
     
         4 . The  lactobacillus  strain-containing food composite according to  claim 1 , wherein the excipient or diluent is a food. 
     
     
         5 . The  lactobacillus  strain-containing food composite according to  claim 4 , wherein the food is one of or a combination of a milk-based drink, tea, coffee, a chewing gum, a tooth-cleaning candy, and dried meat for pets. 
     
     
         6 . A  lactobacillus  strain-containing medical composite comprising:
 at least one  lactobacillus  strain able to inhibit oral pathogens, which is at least one isolated  lactobacillus  strain selected from a group including  Lactobacillus acidophilus  F-1 strain, CCTCC NO: M2011124;  Lactobacillus salivarius  subsp.  salicinius  AP-32 strain, CCTCC NO: M2011127;  Lactobacillus reuteri  GL-104 strain, CCTCC NO: M209138;  Lactobacillus paracasei  GL-156 strain, CCTCC NO: M2014590;  Lactobacillus helveticus  RE-78 strain, CGMCC No. 13513;  Lactobacillus rhamnosus  CT-53 strain, CCTCC NO: M2011129; and  Lactobacillus paracasei  ET-66 strain, CGMCC No. 13514, which are respectively preserved in China Center for Type Culture Collection (CCTCC) and China General Microbiological Culture Collection Center (CGMCC); and   an excipient or diluent, which is medically acceptable.   
     
     
         7 . The  lactobacillus  strain-containing medical composite according to  claim 6 , wherein the  lactobacillus  strain is an active strain. 
     
     
         8 . The  lactobacillus  strain-containing medical composite according to  claim 6 , wherein the  lactobacillus  strain is a deactivated strain. 
     
     
         9 . The  lactobacillus  strain-containing medical composite according to  claim 6 , which is in an oral form or a topical form. 
     
     
         10 . A  lactobacillus  strain-containing oral cleaning composite comprising:
 at least one  lactobacillus  strain able to inhibit oral pathogens, which is at least one isolated  lactobacillus  strain selected from a group including  Lactobacillus acidophilus  F-1 strain, CCTCC NO: M2011124;  Lactobacillus salivarius  subsp.  salicinius  AP-32 strain, CCTCC NO: M2011127;  Lactobacillus reuteri  GL-104 strain, CCTCC NO: M209138;  Lactobacillus paracasei  GL-156 strain, CCTCC NO: M2014590;  Lactobacillus helveticus  RE-78 strain, CGMCC No. 13513;  Lactobacillus rhamnosus  CT-53 strain, CCTCC NO: M2011129; and  Lactobacillus paracasei  ET-66 strain, CGMCC No. 13514, which are respectively preserved in China Center for Type Culture Collection (CCTCC) and China General Microbiological Culture Collection Center (CGMCC); and   an excipient, diluent, or carrier, which is physiologically acceptable.   
     
     
         11 . The  lactobacillus  strain-containing oral cleaning composite according to  claim 10 , wherein the  lactobacillus  strain is an active strain. 
     
     
         12 . The lactobacillus strain-containing oral cleaning composite according to  claim 10 , wherein the  lactobacillus  strain is a deactivated strain. 
     
     
         13 . The  lactobacillus  strain-containing oral cleaning composite according to  claim 10 , wherein the excipient or diluent is a toothpaste, a dental powder, a mouthwash, a fresh-breath spray, a fluorine-coating agent, a false tooth cleaning agent, a pet's tooth gel, or a hairball remedy. 
     
     
         14 . The  lactobacillus  strain-containing oral cleaning composite according to  claim 10 , wherein the carrier is a toothbrush, an interdental brush, a dental floss, an oral cotton stick, or a pet's dental bone.