Formulation for topical wound treatment

Abstract

The present invention relates to new formulations, particularly useful in the topical treatment of skin and orormucosal wounds. Formulations can be either a solution or a gel form consisting of a Polyhexamethylene biguanide as an antimicrobial agent, purified water and a tri-blockcopolymer, particularly a triblockcopolymer of polyethylene oxide and polypropylene oxide, and more particularly a poloxamer.

1 - 15 . (canceled) 
     
     
         16 . A formulation consisting of polyhexamethylene biguanide, purified water and at least one poloxamer for use in the topical and/or oromucosal treatment of wounds. 
     
     
         17 . The formulation according to  claim 16 , consisting of 0.1% polyhexamethylene biguanide by weight, 1.0% poloxamer by weight and 98.9% purified water by weight. 
     
     
         18 . A formulation consisting of polyhexamethylene biguanide, purified water, humectant, gelling agent and at least one poloxamer for use in the topical and/or oromucosal treatment of wounds. 
     
     
         19 . The formulation according to  claim 18 , consisting of 0.1% polyhexamethylenbiguanid (PHMB) by weight, 1.0% poloxamer by weight, 8.6% humectant, 1.8% by weight hydroxyethyl cellulose and 88.5% purified water by weight. 
     
     
         20 . The formulation according to  claim 19 , wherein the poloxamer is selected from poloxamer 124, poloxamer 188, poloxamer 237, poloxamer 338 and poloxamer 407. 
     
     
         21 . The formulation according to  claim 20 , wherein the poloxamer is poloxamer 188.