US2018236015A1PendingUtilityA1
Composition having lactobacillus plantarum strain gmnl-662 for promoting bone regrowth
Est. expiryFeb 20, 2037(~10.6 yrs left)· nominal 20-yr term from priority
A23V 2002/00A61K 35/747A23L 33/135A23Y 2220/67C12R 2001/25C12N 1/205C12N 1/20A23V 2400/169
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Claims
Abstract
A composition having Lactobacillus Plantarum strain GMNL-662 for promoting bone regrowth is provided. The Lactobacillus Plantarum strain GMNL-662 has an ability to promote the expression of osteogenic genes, inhibit the expression of osteoclast related genes, and promote the expression of osteogenesis-related cytokine TGF-β, so that the bone loss is improved.
Claims
exact text as granted — not AI-modifiedWhat is claimed is:
1 . A composition for promoting bone regrowth, comprising Lactobacillus Plantarum strain GMNL-662 deposited in the China Center for Type Culture Collection (CCTCC) with an accession number of CCTCC M2016571.
2 . The composition according to claim 1 , wherein the Lactobacillus Plantarum strain GMNL-662 is a viable strain or a dead strain.
3 . The composition according to claim 1 , wherein the Lactobacillus Plantarum strain GMNL-662 has an ability to improve the expression of osteogenic genes.
4 . The composition according to claim 3 , wherein the osteogenic genes comprise osteocalcin gene.
5 . The composition according to claim 1 , wherein the composition is a pharmaceutical composition, a nutritional supplement, a health food, a medical food, or the combination thereof.
6 . The composition according to claim 1 , wherein the composition is applied to slow down bone loss.Cited by (0)
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