Chemical synthesis

Abstract

Herein are described methods of chemical synthesis.

What is claimed is: 
     
         1 . A method comprising:
 preparing a plurality of individual reaction mixtures by reacting a bait fragment B-x, comprising a preselected bait moiety B and x, wherein x is selected from the group consisting of halo groups, thiols, disulfides, acrylamides, acrylates, vinyl sulfones, epoxides, thiiranes, aziridines, esters, sulfonic acid esters, thioesters, alkynes, and azides, with a plurality of naïve test fragments (y T1, y T2, . . . y Tn), each test fragment comprising y, wherein y is selected from the group consisting of disulfides, thiols, amines, alcohols, phenols, alkynes, and azides, and one of a plurality of naïve test moieties (T1, T2, . . . Tn) under conditions sufficient to form a plurality of n test ligands (B z T1, B z T2, . . . B z Tn), wherein each of B z T1, B z T2, . . . B z Tn is prepared individually in one of a multiplicity of containers and wherein z is a linker formed by reaction of x and y.