Use of an oleogel containing triterpene for healing wounds

Abstract

An oleogel comprising a non-polar liquid and a powder containing triterpene is provided as an oleogel that may be used for healing wounds.

1 - 18 . (canceled) 
     
     
         19 . A method for healing a wound in patient in need thereof, comprising administering to the wound an oleogel comprising a triterpene fraction, wherein the triterpene fraction comprises betulin. 
     
     
         20 . The method of  claim 19 , wherein the oleogel is administered to the wound during the reepithelialization phase. 
     
     
         21 . The method of  claim 19 , wherein the triterpene fraction comprises between 1 weight-percent and 20 weight-percent of the oleogel. 
     
     
         22 . The method of  claim 21 , wherein the triterpene fraction comprises between 6 weight-percent and 12 weight-percent of the oleogel. 
     
     
         23 . The method of  claim 19 , wherein the fraction of betulin in the triterpene fraction is greater than 60 weight-percent. 
     
     
         24 . The method of  claim 19 , wherein the fraction of betulin in the triterpene fraction is greater than 80 weight-percent. 
     
     
         25 . The method of  claim 19 , wherein the triterpene fraction further comprises lupeol. 
     
     
         26 . The method of  claim 25 , wherein the joint fraction of betulin and lupeol in the triterpene is greater than 80 weight-percent in the triterpene fraction. 
     
     
         27 . The method of  claim 25 , wherein the joint fraction of betulin and lupeol is greater than 85 weight-percent in the triterpene fraction. 
     
     
         28 . The method of  claim 19 , wherein the oleogel further comprises a nonpolar liquid. 
     
     
         29 . The method of  claim 28 , wherein the nonpolar liquid is a plant, animal, mineral, or synthetic oil. 
     
     
         30 . The method of  claim 29 , wherein the plant oil is a vegetable oil which is selected from one of the following: sunflower oil, olive oil, avocado oil, and almond oil. 
     
     
         31 . The method of  claim 28 , wherein the nonpolar liquid consists of sunflower oil. 
     
     
         32 . The method of  claim 28 , wherein the nonpolar liquid fraction comprises between 80 weight-percent and 99 weight-percent in relation to the total weight of the oleogel, and wherein the triterprene fraction comprises between 1 weight-percent and 20 weight-percent in relation to the total weight of the oleogel. 
     
     
         33 . The method of  claim 19 , wherein the oleogel further comprises betulinic acid, oleanolic acid, and erythrodiol. 
     
     
         34 . The method of  claim 19 , wherein the patient is a human. 
     
     
         35 . The method of  claim 19 , wherein the method results in more rapid wound healing progress relative to a wound that is not treated with the oleogel. 
     
     
         36 . The method of  claim 19 , wherein the method results in more rapid wound healing progress relative to a wound treated with Vaseline. 
     
     
         37 . The method of  claim 19 , wherein the method results in complete healing of the wound. 
     
     
         38 . A method for promoting reepithelialization of a wound in a patient in need thereof, comprising administering to the wound an oleogel comprising a triterpene fraction, wherein the triterpene fraction comprises betulin.