Oral Care Product and Methods of Use and Manufacture Thereof

Abstract

This invention relates to oral care compositions comprising an effective amount of a basic amino acid in free or salt form, together with an anionic surfactant, and to methods of using and of making such compositions.

1 - 41 . (canceled) 
     
     
         42 . A method of reducing the adhesion of bacteria to tooth surfaces in an oral cavity of a subject, the method comprising treating the oral cavity with an oral care composition comprising a basic amino acid, in free or salt form, and an anionic surfactant. 
     
     
         43 . A method according to  claim 42 , wherein the oral care composition comprises
 a. an effective amount of a basic amino acid, in free or salt form;   b. an anionic surfactant; and   c. an additional agent selected from an effective amount of an antibacterial agent; an effective amount of a fluoride source; an anionic polymer; and combinations thereof.   
     
     
         44 . A method according to  claim 42 , wherein the basic amino acid is arginine. 
     
     
         45 . A method according to  claim 42 , wherein the basic amino acid is in salt form and selected from arginine phosphate, arginine bicarbonate, and arginine hydrochloride. 
     
     
         46 . A method according to  claim 42 , wherein the anionic surfactant is selected from sodium lauryl sulfate and sodium laureth sulfate and mixtures thereof. 
     
     
         47 . A method according to  claim 42 , wherein the anionic surfactant is present in an amount of from about 0.01 to about 10 weight %. 
     
     
         48 . A method according to  claim 42 , wherein the anionic surfactant is present in an amount of from about 0.3 to about 4.5 weight %. 
     
     
         49 . A method according to  claim 42 , wherein the composition further comprises a fluoride source selected from sodium fluoride and sodium monofluorophosphate. 
     
     
         50 . A method according to  claim 42 , further comprising an antibacterial agent. 
     
     
         51 . A method according to  claim 50 , wherein the antibacterial agent is zinc citrate, zinc lactate or a combination thereof. 
     
     
         52 . A method according to  claim 42 , further comprising an anionic polymer. 
     
     
         53 . A method according to  claim 52 , wherein the anionic polymer is a copolymer of methyl vinyl ether and maleic anhydride. 
     
     
         54 . A method according to  claim 42 , wherein the composition is a dentifrice comprising
 a. an effective amount of a salt of a basic amino acid selected from arginine bicarbonate arginine phosphate and arginine hydrochloride;   b. an effective amount of a soluble fluoride salt selected from sodium fluoride and sodium monofluophosphate;   c. an anionic surfactant selected from sodium laurel sulfate and sodium laureth sulfate.   
     
     
         55 . A method according to  claim 42 , wherein the composition further comprises xylitol. 
     
     
         56 . A method according to  claim 42 , comprising a particulate material selected from dicalcium phosphate, silica and calcium carbonate. 
     
     
         57 . A method according to  claim 42 , wherein the radioactive dentin abrasion (RDA) is less than about 150. 
     
     
         58 . A method according to  claim 42 , wherein the composition is in the form of a toothpaste further comprising one or more of water; abrasives, surfactants, foaming agents, vitamins, polymers, enzymes, humectants, thickeners, antimicrobial agents, preservatives, flavorings, colorings and/or combinations thereof.