Administration apparatus

Abstract

Provided is an administration apparatus for administering a dosing liquid. The administration apparatus includes a storage unit storing the dosing liquid, a drive unit imparting administration energy and a pressurization unit pressurizing the stored dosing liquid with the administration energy. The administration apparatus also includes an injection unit injecting the pressurized liquid to an object region through an injection port. In a pressure transition of the dosing liquid at the injection port, a vibration in the pressure transition reaches a converged state from a rising time of pressure. Furthermore, a ratio of a peak value of an initial vibration element to a peak value of subsequent vibration elements other than the first vibration element is higher than 1 and equal to or lower than a prescribed first ratio. As a result, invasiveness to the object region during administration is reduced.

1 . An administration apparatus which administers a dosing liquid containing a prescribed substance to an object region, the administration apparatus comprising:
 a storage unit which stores the dosing liquid;   a drive unit which imparts administration energy;   a pressurization unit which pressurizes the dosing liquid stored in the storage unit with the administration energy in the drive unit; and   an injection unit which injects the dosing liquid having been pressurized by the pressurization unit to the object region through an injection port,   wherein the pressurization unit pressurizes the dosing liquid so that, in a pressure transition of the dosing liquid at the injection port in response to imparting the administration energy, a vibration in the pressure transition reaches a converged state within a prescribed period of time from a rising time of pressure, and a ratio of a peak value of an initial first vibration element in the vibration within the prescribed period of time to a peak value of subsequent vibration elements other than the first vibration element is higher than 1 and equal to or lower than a prescribed first ratio.   
     
     
         2 . The administration apparatus according to  claim 1 , wherein the drive unit includes at least a high-energy substance and generates the administration energy by burning the high-energy substance. 
     
     
         3 . The administration apparatus according to  claim 1 , wherein the first vibration element is a vibration that reaches pressure equal to or higher than 10 MPa that is the peak value within 0.5 msec from the rising time. 
     
     
         4 . The administration apparatus according to  claim 1 , wherein within the prescribed period of time from the rising time, pressure of the dosing liquid reaches the converged state while vibrating in a damped manner at a frequency belonging to a prescribed frequency range. 
     
     
         5 . The administration apparatus according to  claim 4 , wherein the prescribed frequency range is 500 to 10000 Hz. 
     
     
         6 . The administration apparatus according to  claim 1 , wherein a total amplitude of the other vibration elements included in the vibration in the prescribed period of time is equal to or less than 15 MPa. 
     
     
         7 . An administration apparatus which administers a dosing liquid containing a prescribed substance to an object region, the administration apparatus comprising:
 a storage unit which stores the dosing liquid in a storage chamber;   a drive unit which imparts administration energy;   a pressurization unit which pressurizes the dosing liquid stored in the storage unit with the administration energy in the drive unit; and   an injection unit which injects the dosing liquid having been pressurized by the pressurization unit to the object region through an injection port,   wherein the pressurization unit pressurizes the dosing liquid so that, in a pressure transition of the dosing liquid at the injection port in response to imparting the administration energy, a vibration in the pressure transition dampens over time within a prescribed period of time from a rising time of pressure and the vibration within the prescribed period of time is a damped vibration at a frequency belonging to a prescribed frequency range.   
     
     
         8 . The administration apparatus according to  claim 7 , wherein the drive unit includes at least a high-energy substance and generates the administration energy by burning the high-energy substance. 
     
     
         9 . The administration apparatus according to  claim 7 , wherein the prescribed frequency range is 500 to 10000 Hz. 
     
     
         10 . The administration apparatus according to  claim 7 , wherein a ratio of a peak value of an initial first vibration element in the vibration within the prescribed period of time to a peak value of subsequent vibration elements other than the first vibration element is higher than 1 and equal to or lower than a prescribed first ratio. 
     
     
         11 . The administration apparatus according to  claim 10 , wherein the first vibration element is a vibration that reaches pressure equal to or higher than 10 MPa that is the peak value within 0.5 msec from the rising time. 
     
     
         12 . The administration apparatus according to  claim 7 , wherein a total amplitude of vibration elements other than the initial first vibration element in the vibration within the prescribed period of time is equal to or lower than 15 MPa. 
     
     
         13 . The administration apparatus according to  claim 1 , wherein the prescribed period of time is a period of 2 msec or less from the rising time. 
     
     
         14 . The administration apparatus according to  claim 13 , wherein the prescribed period of time is a period of 1.5 msec or less from the rising time. 
     
     
         15 . The administration apparatus according to  claim 2 , further comprising:
 a gas generating agent which generates prescribed gas by combustion and which is arranged at a position exposed to combustion products generated by the combustion of the high-energy substance,   wherein the pressurization unit further pressurizes the dosing liquid by energy created by the combustion of the gas generating agent in a vicinity of a time at which the prescribed period of time has elapsed from the rising time of pressure of the dosing liquid.   
     
     
         16 . The administration apparatus according to  claim 15 , wherein:
 when the administration energy is defined as first administration energy, and   energy created by the combustion of the gas generating agent is defined as second administration energy,   a peak value in a pressure transition of the dosing liquid by the second administration energy is equal to or higher than a peak value in a pressure transition excluding the first vibration element in the pressure transition of the dosing liquid by the first administration energy.   
     
     
         17 . The administration apparatus according to  claim 1 , wherein the administration apparatus administers the dosing liquid to the object region from the injection port without involving an introduction unit. 
     
     
         18 . The administration apparatus according to  claim 7 , wherein the prescribed period of time is a period of 2 msec or less from the rising time. 
     
     
         19 . The administration apparatus according to  claim 18 , wherein the prescribed period of time is a period of 1.5 msec or less from the rising time. 
     
     
         20 . The administration apparatus according to  claim 8 , further comprising:
 a gas generating agent which generates prescribed gas by combustion and which is arranged at a position exposed to combustion products generated by the combustion of the high-energy substance,   wherein the pressurization unit further pressurizes the dosing liquid by energy created by the combustion of the gas generating agent in a vicinity of a time at which the prescribed period of time has elapsed from the rising time of pressure of the dosing liquid.   
     
     
         21 . The administration apparatus according to  claim 20 , wherein:
 when the administration energy is defined as first administration energy, and   energy created by the combustion of the gas generating agent is defined as second administration energy,   a peak value in a pressure transition of the dosing liquid by the second administration energy is equal to or higher than a peak value in a pressure transition excluding the first vibration element in the pressure transition of the dosing liquid by the first administration energy.   
     
     
         22 . The administration apparatus according to  claim 7 , wherein the administration apparatus administers the dosing liquid to the object region from the injection port without involving an introduction unit.