US2018339012A1PendingUtilityA1
Methods for treatment of atherosclerosis
Assignee: STEALTH BIOTHERAPEUTICS CORPPriority: Aug 2, 2012Filed: Dec 20, 2017Published: Nov 29, 2018
Est. expiryAug 2, 2032(~6.1 yrs left)· nominal 20-yr term from priority
A61K 45/06A61K 31/351A61K 31/215A61K 31/366A61P 9/10A61K 31/505A61K 31/22A61K 38/07A61K 31/404A61K 31/40A61K 2300/00
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Abstract
Disclosed herein are methods and compositions for preventing or treating atherosclerosis in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide and in some applications, a second active agent chemically linked to the peptide, to subjects in need thereof.
Claims
exact text as granted — not AI-modified1 . A method for treating atherosclerosis in a mammalian subject in need thereof, the method comprising administering an effective amount of (i) a peptide D-Arg-2′6′-Dmt-Lys-Phe-NH 2 or a pharmaceutically acceptable salt thereof and (ii) an antihyperlipidemic drug, wherein the peptide and the antihyperlipidemic drug are chemically linked.
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