Flow diversion device

Abstract

A flow diversion device for the treatment of intracranial aneurysms and other medical conditions is disclosed. The flow diversion device may include a generally tubular wire stent frame formed from a plurality of zig-zag shaped wire elements that are coupled together. The device further includes a base layer of graft material coupled to the wire stent frame and surrounding at least a portion thereof, the wire stent frame maintaining the base layer in an open condition. In some embodiments, the base layer may be formed of porous graft material having a plurality of pores formed thereon to provide a passageway for a small blood flow to maintain the long term patency of important small side branches, while also reducing blood flow to the aneurysm to promote occlusion and avoid potential rupture.

1 - 20 . (canceled) 
     
     
         21 . A flow diversion device comprising:
 a tubular wire stent frame formed from a plurality of wire elements, each wire element in the plurality of wire elements having a zig-zag pattern shape, wherein adjacent wire elements form a plurality of junctions, and wherein a first set of the plurality of junctions are coupled together and a second set of the plurality of junctions are not coupled together; and   a base layer attached to the wire stent frame and surrounding at least a central portion of the tubular wire stent, the base layer formed of a porous graft material and having a plurality of perforations formed therethrough in a predetermined spaced-apart pattern.   
     
     
         22 . The flow diversion device of  claim 21 , wherein the plurality of perforations are incisions. 
     
     
         23 . The flow diversion device of  claim 22 , wherein the incisions are half-circles. 
     
     
         24 . The flow diversion device of  claim 21 , wherein the plurality of junctions formed between adjacent wire elements are alternately coupled. 
     
     
         25 . The flow diversion device of  claim 21 , wherein the plurality of junctions are formed along a radial direction of the tubular wire stent frame. 
     
     
         26 . The flow diversion device of  claim 21 , where a distal portion and a proximal portion of the tubular wire stent frame are free of the base layer. 
     
     
         27 . The flow diversion device of  claim 26 , wherein the plurality of wire elements form a plurality of diamond shapes along the longitudinal direction of the tubular wire stent frame, and wherein at least 1½ diamonds of the distal portion and the proximal portion of the tubular wire stent frame are free of the base layer. 
     
     
         28 . The flow diversion device of  claim 21 , wherein the wire stent frame supports the base layer in an open condition, and wherein the plurality of perforations prevent excess billowing of the base layer in the open condition while blood flows through the flow diversion device. 
     
     
         29 . The flow diversion device of  claim 21 , further comprising a jacket attached to and surrounding the base layer. 
     
     
         30 . The flow diversion device of  claim 21 , wherein a proximal end and a distal end of the wire stent frame further comprise a radiopaque marker. 
     
     
         31 . A flow diversion device comprising:
 a tubular wire stent frame formed from a plurality of wire elements, each wire element in the plurality of wire elements having a zig-zag pattern; and   a base layer attached to the wire stent frame and surrounding at least a portion thereof, the base layer formed or porous graft material having a plurality of perforations formed therethrough,   wherein the wire stent frame supports the base layer in an open condition, and   wherein the plurality of perforations prevent excess billowing of the base layer in the open condition while blood flows through the flow diversion device.   
     
     
         32 . The flow diversion device of  claim 31 , wherein the plurality of wire elements form a plurality of diamond shapes along the longitudinal direction of the tubular wire stent frame, and wherein at least 1½ diamonds of the distal portion and the proximal portion of the tubular wire stent frame are free of the base layer. 
     
     
         33 . The flow diversion device of  claim 31 , wherein the plurality of perforations are incisions. 
     
     
         34 . The flow diversion device of  claim 33 , wherein the incisions are half-circles. 
     
     
         35 . The flow diversion device of  claim 31 , further comprising an anchor stent attached to the wire stent frame. 
     
     
         36 . The flow diversion device of  claim 35 , wherein the anchor stent is attached to a guidewire and extends from a distal end of the wire stent frame. 
     
     
         37 . The flow diversion device of  claim 36 , wherein the anchor stent further comprises a plurality of wire elements, each wire element in the plurality of wire elements having a zig-zag pattern, and a plurality of connector struts that couple the plurality of wire elements to the guidewire. 
     
     
         38 . The flow diversion device of  claim 37 , wherein the anchor stent further comprises a plurality of radiopaque markers on an end opposite the connector struts.