Omega-3 compositions

Abstract

The present invention relates to compositions comprising omega-3 fatty acid derivatives, and in particular to compositions comprising omega-3 phospholipids in combination with other omega-3 derivatives.

1 . A composition comprising a mixture of phospholipid compounds having the following structure: 
       
         
           
           
               
               
           
         
         wherein R1 and R2 are selected from the group consisting of a fatty acid moiety and H and R3 is H or a choline, ethanolamine, inositol and serine moiety, said mixture of phospholipid compounds comprising more than about 90% choline moieties at position R3 and more than about 30% w/w omega-3 fatty acid moieties, wherein more than about 90% w/w of said omega-3 fatty acid moieties are at position R2, 
         and 
         a mixture of omega-3 fatty acid derivatives selected from the group consisting of: 
         a mixture of glyceride compounds having the following structure: 
       
       
         
           
           
               
               
           
         
         wherein at least one of either R1, R2, and R3 is a an omega-3 fatty acid moiety, and the other two of either R1, R2 and R3 may H or a fatty acid moiety, and 
         esters and free fatty acids of omega-3 fatty acids, and combinations thereof. 
       
     
     
         2 . The composition of  claim 1 , wherein said mixture of omega-3 fatty acid derivatives comprises at least 30% omega-3 fatty acid moieties on a w/w basis. 
     
     
         3 . The composition of  claim 1 , wherein said mixture of omega-3 fatty acid derivatives comprises at least 50% omega-3 fatty acid moieties on a w/w basis. 
     
     
         4 . The composition of  claim 1 , wherein said mixture of omega-3 fatty acid derivatives comprises at least 65% omega-3 fatty acid moieties on a w/w basis. 
     
     
         5 . The composition of  claim 1 , wherein said composition comprises at least 80% omega-3 fatty acid moieties on a w/w basis. 
     
     
         6 . The composition of  claim 1 , wherein said omega-3 fatty acid moieties are selected from the group consisting of eicosapentaenoic acid, docosahexaenoic acid, and combinations thereof. 
     
     
         7 . The composition of  claim 1 , wherein said composition comprises at least 5% w/w of said phospholipid compounds. 
     
     
         8 . The composition of  claim 1 , wherein said composition comprises at least 25% w/w of said phospholipid compounds. 
     
     
         9 . The composition of  claim 1 , wherein said composition comprises at least 50% w/w of said phospholipid compounds. 
     
     
         10 . The composition of  claim 1 , wherein said composition comprises at least 70% w/w of said phospholipid compounds. 
     
     
         11 . The composition of  claim 7 , wherein said omega-3 moieties in said mixture of mixture of phospholipid compounds are eicosapentaenoic acid and said docosahexaenoic acid and wherein said eicosapentaenoic acid and said docosahexaenoic acid are present in a ratio of eicosapentaenoic acid:docosahexaenoic acid of from about 1:1 to about 3:1. 
     
     
         12 . The composition of  claim 7 , wherein said composition comprises at least 10% ethyl esters comprising said omega-3 fatty acid moieties. 
     
     
         13 . The composition of  claim 7 , wherein said composition comprises at least 20% ethyl esters comprising said omega-3 fatty acid moieties. 
     
     
         14 . The composition of  claim 7 , wherein said composition comprises at least 30% ethyl esters comprising said omega-3 fatty acid moieties. 
     
     
         15 . The composition of  claim 7 , wherein said composition comprises at least 50% ethyl esters comprising said omega-3 fatty acid moieties. 
     
     
         16 . The composition of  claim 7 , wherein said composition comprises at least 70% ethyl esters comprising said omega-3 fatty acid moieties. 
     
     
         17 . The composition of  claim 7 , wherein said composition comprises at least 90% ethyl esters comprising said omega-3 fatty acid moieties. 
     
     
         18 . The composition of  claim 7 , wherein said composition comprises at least 10% glyceride compounds comprising said omega-3 fatty acid moieties. 
     
     
         19 . The composition of  claim 7 , wherein said composition comprises at least 30% glyceride compounds comprising said omega-3 fatty acid moieties. 
     
     
         20 . The composition of  claim 7 , wherein said composition comprises at least 50% glyceride compounds comprising said omega-3 fatty acid moieties. 
     
     
         21 . The composition of  claim 7 , wherein said composition comprises at least 70% glyceride compounds comprising said omega-3 fatty acid moieties. 
     
     
         22 . The composition of  claim 7 , wherein said composition comprises at least 90% glyceride compounds comprising said omega-3 fatty acid moieties. 
     
     
         23 . The composition of any of  claim 7 , wherein said composition comprises at least 10% omega-3 free fatty acids. 
     
     
         24 . The composition of  claim 7 , wherein said composition comprises at least 30% omega-3 free fatty acids. 
     
     
         25 . The composition of  claim 7 , wherein said composition comprises at least 50% omega-3 free fatty acids. 
     
     
         26 . The composition of  claim 7 , wherein said composition comprises at least 70% omega-3 free fatty acids. 
     
     
         27 . The composition of  claim 7 , wherein said composition comprises at least 90% omega-3 free fatty acids. 
     
     
         28 . The composition of  claim 7 , wherein said omega-3 fatty acid moieties or free fatty acids are selected from the group consisting of eicosapentaenoic acid and docosahexaenoic acid and combinations thereof. 
     
     
         29 . The composition of  claim 28 , wherein said eicosapentaenoic acid and said docosahexaenoic acid are present in a ratio of eicosapentaenoic acid:docosahexaenoic acid of from about 1:1 to about 3:1. 
     
     
         30 . The composition of  claim 1 , wherein said composition comprises astaxanthin. 
     
     
         31 . The composition of  claim 1 , wherein said composition comprises at least a second antioxidant. 
     
     
         32 . The composition of  claim 1 , wherein said composition is partially or totally derived from krill. 
     
     
         33 . The composition of  claim 1 , wherein said composition is provided in a formulation selected from the group consisting of a capsule, a tablet, a liquid, a powder, an emulsion, a dietary supplement, a nutritional supplement, a beverage and a functional food.