US2019064179A1PendingUtilityA1
Beta-glucan assay methods
Est. expiryDec 5, 2033(~7.4 yrs left)· nominal 20-yr term from priority
Inventors:Nandita BoseMary A. AntonysamyKeith B. GordenRichard M. WalshMichael E. DanielsonPeter Maimonis
G01N 2800/24C07K 16/16G01N 33/56961A61K 39/0002G01N 2400/24G01N 33/53A61P 37/02G01N 33/6854C07K 16/14
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Abstract
This disclosure provides, in one aspect, a method for analyzing a sample from a subject for a biomarker that is indicative of the subject's immune response to β-glucan. Generally, the method includes obtaining a biological sample from a subject, analyzing the sample for a biomarker anti-β-glucan antibody compared to a reference standard, computing a Relative Antibody Unit (RAU) value for anti-β-glucan antibody in the sample, and identifying the subject as biomarker positive if the RAU value is greater than a predetermined RAU value for the biomarker anti-β-glucan antibody.
Claims
exact text as granted — not AI-modified1 . A method comprising:
obtaining a biological sample from a subject; analyzing the sample for a biomarker anti-β-glucan antibody compared to a reference standard; computing a Relative Antibody Unit (RAU) value for anti-β-glucan antibody in the sample; and identifying the subject as biomarker positive if the RAU value is greater than a predetermined RAU value for the biomarker anti-β-glucan antibody.
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