Filtration System for Preparation of Fluids for Medical Applications

Abstract

A treatment system for performing a treatment on a patient may include a treatment fluid preparation device having a pump connected by a fluid channel to a reservoir of a source fluid, the pump conveying the source fluid from the reservoir, through a filter, and combining the source fluid with a concentrate by pumping the source fluid with the concentrate to form a treatment fluid in a batch container. The treatment fluid preparation device may have a controller that controls a heater, the pump, and a memory. The controller starts the heater to warm the treatment fluid in the batch container at a time that is responsive to the treatment time stored in the memory. The controller also detects a pressure property of the filter to determine its integrity and outputs an indication of a failed batch if the pressure property indicates the integrity of the filter is insufficient.

What is claimed is: 
     
         1 . A treatment system for performing a treatment on a patient, the treatment system comprising:
 a treatment fluid preparation device connected to a source of fluid;   the source of fluid including one or more of: a container of sterile or non-sterile replacement fluid, one or more containers of constituents which, when combined, form a replacement fluid, and a continuous source such as a water tap;   the source of fluid being connected by a line to convey fluid a filter and into a mixing container;   the source of fluid including a batch container elevated at a predefined height to provide a predefined head pressure;   the batch container being a disposable container or a number of disposable containers interconnected to permit flow into and out of them;   the treatment system including a pump to pump a fluid across the filter into the mixing container.   
     
     
         2 . The system of  claim 1 , wherein the pump is regulated responsively to a magnitude of the transmembrane pressure. 
     
     
         3 . The system of  claim 1 , wherein the pump is regulated to limit a transmembrane pressure of the filter. 
     
     
         4 . The system of  claim 1 , further comprising a controller that controls the administration of heat to the mixing container. 
     
     
         5 . The system of  claim 1 , further comprising a treatment component that withdraws a treatment fluid from the mixing container and conveys treatment fluid to and from a patient. 
     
     
         6 . A treatment system for performing a treatment on a patient, the treatment system comprising:
 a treatment fluid preparation device connected to a source of fluid;   the source of fluid including one or more of: a container of sterile or non-sterile replacement fluid, one or more containers of constituents which, when combined, form a replacement fluid, and a continuous source such as a water tap;   the source of fluid being connected by a line to convey fluid a filter and into a mixing container;   the batch container being a disposable container or a number of disposable containers interconnected to permit flow into and out of them;   the treatment system having a controller that controls a pump that regulates the flow of fluid from the source of fluid to the mixing container;   a treatment component that withdraws a treatment fluid from the mixing container and conveys treatment fluid to and from a patient.   
     
     
         7 . The system of  claim 6 , wherein the pump is regulated responsively to a magnitude of the transmembrane pressure. 
     
     
         8 . The system of  claim 6 , wherein the treatment component has a further controller which further controller controls the pump of the treatment fluid preparation device. 
     
     
         9 . A treatment system for performing a treatment on a patient, the treatment system, comprising:
 a treatment fluid preparation device having a pump connected by a fluid channel to a source of fluid;   the pump and fluid channel being configured convey the source fluid through a filter, to combine water and concentrated fluids effective to form a batch of treatment fluid in a mixing container by pumping them from the source of fluid through the fluid channel;   the treatment fluid preparation device having a controller with a memory configured to control a heater and the pump;   the controller being configured to start a treatment when the batch of treatment fluid reaches a target temperature;   the controller controlling the pump to administer heated treatment fluid from the batch container to a patient at a predefined flow rate and to withdraw waste fluid from the patient.   
     
     
         10 . The system of  claim 9 , wherein the controller is further configured to detect exhaustion of the treatment fluid in the batch container and the controller is further configured to halt the heater upon completion of administration of the treatment fluid. 
     
     
         11 . The system of  claim 9 , wherein the controller is configured to halt the pump after displacement of a predetermined volume of the treatment fluid. 
     
     
         12 . The system of  claim 9 , wherein the controller is configured to detect a pressure property of the filter to determine its integrity and to output an indication of a failed batch responsively to the pressure property indication. 
     
     
         13 . The system of  claim 17 , wherein the pressure property includes a transmembrane pressure. 
     
     
         14 . The system of  claim 9 , wherein the controller is configured to maintain a balance between the treatment fluid administered to the patient and waste fluids withdrawn from the patient. 
     
     
         15 . The system of  claim 9 , wherein the controller is configured to measure a conductivity of the treatment fluid. 
     
     
         16 . The system of  claim 15 , wherein the controller is configured to measure the conductivity of the treatment fluid before the treatment. 
     
     
         17 . The system of  claim 9 , the concentrate is stored in a concentrate container and the concentrate container and the batch container are interconnected by tubing containing a sterile filter. 
     
     
         18 . The system of  claim 9 , wherein the water includes purified water. 
     
     
         19 . The system of  claim 9 , wherein the concentrated fluids are effective to form, when diluted with the water, a dialysate. 
     
     
         20 . The system of  claim 9 , wherein the controller has a user interface connected to the controller, the user interface being configured to receive user input specifying the treatment time. 
     
     
         21 . The system of  claim 9 , where in the source fluid includes a batch container from which source fluid is drawn. 
     
     
         22 . A treatment fluid preparation system, comprising:
 a first fluid device connected to a water tap connected by a fluid channel to a filter and in turn to a batch container;   the first fluid device having a controller that controls a pump in the fluid channel that controls the flow of water through the filter;   a second fluid device controller controlling a pump of the second fluid device to receive fluid from the batch container.   
     
     
         23 . The system of  claim 22 , wherein the second fluid device is connected to the batch container, the second fluid device having a controller connected by a communications channel which includes a wire harness, separate wires, a bus, a wireless channel, or a communications/power transmission device. 
     
     
         24 . The system of  claim 23 , wherein the second fluid device controller controls the first fluid device pump without sending information to the first fluid device controller. 
     
     
         25 . A treatment system for performing a treatment on a patient, the treatment system, comprising:
 a treatment fluid preparation device having a pump connected by a fluid channel to a source of fluid;   the pump and fluid channel being configured convey the source fluid through a filter, to combine water and concentrated fluids effective to form a batch of treatment fluid in a mixing container by pumping them from the source of fluid through the fluid channel;   the treatment fluid preparation device having a controller with a memory which is configured to control a heater and the pump;   the controller being configured to start the heater to warm the treatment fluid in the mixing container at a time that is responsive to the treatment time stored in the memory;   the controller controlling the pump to administer heated treatment fluid from the batch container to a patient at a predefined flow rate and to withdraw waste fluid from the patient.   
     
     
         26 . The system of  claim 25 , wherein the controller is further configured to detect exhaustion of the treatment fluid in the batch container and the controller is further configured to halt the heater upon completion of administration of the treatment fluid. 
     
     
         27 . The system of  claim 25 , wherein the controller is configured to halt the pump after displacement of a predetermined volume of the treatment fluid. 
     
     
         28 . The system of  claim 25 , wherein the controller is configured to detect a pressure property of the filter to determine its integrity and to output an indication of a failed batch responsively to the pressure property indication. 
     
     
         29 . The system of  claim 33 , wherein the pressure property includes a transmembrane pressure. 
     
     
         30 . The system of  claim 25 , wherein the controller is configured to maintain a balance between the treatment fluid administered to the patient and waste fluids withdrawn from the patient. 
     
     
         31 . The system of  claim 25 , wherein the controller is configured to measure a conductivity of the treatment fluid. 
     
     
         32 . The system of  claim 25 , wherein the controller is configured to measure the conductivity of the treatment fluid before the treatment. 
     
     
         33 . The system of  claim 25 , the concentrate is stored in a concentrate container and the concentrate container and the batch container are interconnected by tubing containing a sterile filter. 
     
     
         34 . The system of  claim 25 , wherein the water includes purified water. 
     
     
         35 . The system of  claim 25 , wherein the concentrated fluids are effective to form, when diluted with the water, a dialysate. 
     
     
         36 . The system of  claim 25 , wherein the controller has a user interface connected to the controller, the user interface being configured to receive user input specifying the treatment time. 
     
     
         37 . The system of  claim 25 , where in the source fluid includes a batch container from which source fluid is drawn.