Kits and methods of using ascorbates to modify polysaccharide fillers and delivery systems

Abstract

Embodiments of the present invention are directed to kits, compositions and methods for modifying and altering polysaccharide fillers and drug delivery systems with the application of an ascorbate.

1 . A method of altering or modifying a mass comprising a polysaccharide comprising the steps of:
 a. administering an effective amount of an ascorbate to the mass.   
     
     
         2 . The method of  claim 1  wherein said polysaccharide has one or more sugars selected from the group consisting of D-galactose and 3, 6-anhydro-L-galactopyranose. 
     
     
         3 . The method of  claim 1  wherein said ascorbate is ascorbic acid. 
     
     
         4 . The method of  claim 1  wherein said polysaccharide is an agarose. 
     
     
         5 . The method of  claim 1  wherein said mass is a dermal filler. 
     
     
         6 . The method of  claim 1  wherein said mass is a deliver vehicle for one or more drugs. 
     
     
         7 . The method of  claim 1  wherein said ascorbate is administered to the mass in vivo. 
     
     
         8 . The method of  claim 1  wherein said ascorbate is administered with the polysaccharide. 
     
     
         9 . A drug delivery system comprising a polysaccharide and ascorbate for said held in a vessel for reconstitution. 
     
     
         10 . The drug delivery system of  claim 9  further comprising drug. 
     
     
         11 . A kit for performing dermal filling procedures comprising:
 a. a polysaccharide for forming a mass in the body of an animal;   b. an ascorbate for altering said polysaccharide, for administration with said polysaccharide or to said mass held in the body to effect a modification of said mass.   
     
     
         12 . The kit of  claim 11  wherein said polysaccharide has one or more sugars selected from the group consisting of D-galactose and 3, 6-anhydro-L-galactopyranose. 
     
     
         13 . The kit of  claim 11  wherein said ascorbate is ascorbic acid. 
     
     
         14 . The kit of  claim 11  wherein said polysaccharide is an agarose.