Compositions and methods for prognosis of ovarian cancer

Abstract

Described herein are compositions and methods for the prediction of the prognosis of ovarian cancer subjects. The present invention further provides methods for distinguishing between histological subtypes of ovarian cancer tumors, and also methods and compositions for the treatment or prevention of ovarian cancer. Specifically the invention relates to microRNA molecules associated with said methods and compositions, as well as various nucleic acid molecules relating thereto or derived therefrom.

1 . A method of determining the prognosis of ovarian cancer in a subject comprising:
 (a) obtaining a biological sample from the subject;   (b) determining the expression level in said sample of a nucleic acid sequence selected from the group consisting of SEQ ID NOS: 1-71 and sequences at least about 80% identical thereto; and   (c) comparing said expression level to a threshold expression level,   
       wherein comparison of said expression level of said nucleic acids to said threshold expression level is predictive of the prognosis of said ovarian-cancer subject. 
     
     
         2 .- 44 . (canceled)