US2019142790A1PendingUtilityA1
Isoflavonoid compounds and methods for the treatment of cancer
Est. expiryNov 1, 2030(~4.3 yrs left)· nominal 20-yr term from priority
A61P 35/00A61P 43/00A61P 35/02A61P 15/08C07D 311/58A61K 9/5161A61K 31/353A61K 45/06A61K 31/555A61K 31/337A61K 9/0019A61K 47/40A61K 33/24A61K 33/243
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exact text as granted — not AI-modified1 .- 15 . (canceled)
16 . A compound that is cis-3-(4-hydroxyphenyl)-4-(4-hydroxyphenyl)-8-methylchroman-7-ol.
17 . A kit comprising a compound that is cis-3-(4-hydroxyphenyl)-4-(4-hydroxyphenyl)-8-methylchroman-7-ol.
and a sealable, plastic infusion bag.
18 . A method of treating cancer in an individual in need of cancer therapy, the method comprising administering to the individual a compound that is cis-3-(4-hydroxyphenyl)-4-(4-hydroxyphenyl)-8-methylchroman-7-ol.
19 . The method of claim 18 , wherein the compound increases or induces sensitivity of the cancer to a chemotherapeutic agent, anti-cancer agent, or radiation therapy.
20 . The method of claim 18 , wherein the cancer has lost sensitivity to a chemotherapeutic agent, anti-cancer agent, or radiation therapy.
21 . The method of claim 18 , wherein said cancer is selected from the group consisting of bladder cancer, breast cancer, colon cancer, rectal cancer, endometrial cancer, kidney cancer, leukemia, lung cancer, melanoma, non-Hodgkin lymphoma, ovarian cancer, pancreatic cancer, prostate cancer, thyroid cancer, and cancers of the brain.
22 . The method of claim 18 , wherein said cancer is human breast cancer or ovarian cancer.
23 . The method of claim 18 , wherein the method further comprises administering an additional anti-cancer agent selected from the group consisting of cisplatin, carboplatin, paclitaxel, gemcitabine, doxorubicin, epirubicin, cyclophosphamide, capecitabine, 5-fluorouracil, vinorelbine, trastuzumab, or bevacizumab.Join the waitlist — get patent alerts
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