Mixtures of sabadilla alkaloids and neem oil and uses thereof

Abstract

The present invention is directed to pesticidal mixtures comprising sabadilla alkaloids and neem oil and methods of controlling pests including insects and mites by application of pesticidal mixtures comprising sabadilla alkaloids and neem oil.

What is claimed is: 
     
         1 . A pesticidal mixture comprising an effective amount of sabadilla alkaloids and neem oil. 
     
     
         2 . The mixture of  claim 1 , wherein the sabadilla alkaloids are derived from  Schoenocaulon officinale.    
     
     
         3 . The mixture of  claim 1 , wherein the sabadilla alkaloids are veratridine and cevadine. 
     
     
         4 . The mixture of  claim 1 , further comprising one or more excipients selected from the group consisting of solvents, anti-caking agents, stabilizers, defoamers, slip agents, humectants, dispersants, wetting agents, thickening agents, emulsifiers, penetrants, adjuvants, synergists, polymers, propellants and/or preservatives. 
     
     
         5 . The mixture of  claim 1 , wherein the sabadilla alkaloid is present in the mixture at a concentration from about 0.01% to about 1% w/w, wherein w/w denotes weight by total weight of the mixture. 
     
     
         6 . The mixture of  claim 1 , wherein the sabadilla alkaloid is present in the mixture at a concentration from about 0.025% to about 0.5% w/w, wherein w/w denotes weight by total weight of the mixture. 
     
     
         7 . The mixture of  claim 1 , wherein the neem oil is present in the mixture at a concentration from about 0.1% to about 10% w/w, wherein w/w denotes weight by total weight of the mixture. 
     
     
         8 . The mixture of  claim 1 , wherein the neem oil is present in the mixture at a concentration from about 0.5% to about 4% w/w, wherein w/w denotes weight by total weight of the mixture. 
     
     
         9 . A method of controlling a pest comprising applying a pesticidal mixture comprising an effective amount of sabadilla alkaloids and neem oil to the pest or the pest's environment. 
     
     
         10 . The method of  claim 9 , wherein the pest is at least one of an insect and a mite. 
     
     
         11 . The method of  claim 9 , wherein the pest is selected from the group consisting of aphids (Homoptera), whiteflies (Hemiptera), thrips (Thysanoptera), bed bugs (Hemiptera), fleas (Siphonaptera), caterpillars/worms (Lepidoptera), beetles (Coleoptera), cockroaches (Blattodea), flies (Diptera), ants (Hymenoptera), and mites (Acari). 
     
     
         12 . The method of  claim 9 , wherein the pest is selected from the group consisting of common bed bugs ( Cimex lectularius ), green peach aphids ( Myzus persicae ), house fly ( Musca domestica ), yellow fever mosquito ( Aedes aegypti ), southern house mosquito ( Culex quinquefasciatus ), African malaria mosquito ( Anopheles gambiae ), common malaria mosquito ( Anopheles quadrimaculatus ) and German cockroach ( Blattella germanica ). 
     
     
         13 . The method of  claim 9 , wherein the sabadilla alkaloid is applied at a rate from about 1 to about 1,000 grams per hectare. 
     
     
         14 . The method of  claim 9 , wherein the sabadilla alkaloid is applied at a rate from about 10 to about 700 grams per hectare. 
     
     
         15 . The method of  claim 9 , wherein the sabadilla alkaloid is applied at a rate from about 22 to about 105 grams per hectare. 
     
     
         16 . The method of  claim 9 , wherein the neem oil is applied at a rate from about 10 to about 10,000 grams per hectare. 
     
     
         17 . The method of  claim 9 , wherein the neem oil is applied at a rate from about 500 to about 8,000 grams per hectare. 
     
     
         18 . The method of  claim 9 , wherein the neem oil is applied at a rate from about 918 to about 7,344 grams per hectare.