Oral Care Compositions and Methods of Using the Compositions

Abstract

An oral care composition comprising zinc phosphate and stannous fluoride.

We claim: 
     
         1 . An oral care composition, comprising:
 an orally acceptable carrier;   zinc phosphate; and   stannous fluoride.   
     
     
         2 . The oral care composition of  claim 1 , wherein the zinc phosphate is a preformed salt of zinc phosphate. 
     
     
         3 . The oral care composition of  claim 1 , wherein zinc phosphate is present in an amount sufficient so that the stannous fluoride dissociates to provide a therapeutically effective amount of stannous ions in aqueous solution. 
     
     
         4 . The oral care composition of  claim 1 , wherein the amount of zinc phosphate is from 0.05 to 5% by weight, relative to the weight of the oral care composition. 
     
     
         5 . The oral care composition of  claim 1 , wherein the amount of the stannous fluoride is from 0.05% to 5% by weight, relative to the weight of the oral care composition. 
     
     
         6 . The oral care composition of  claim 1 , wherein the amount of the water is about 12% by weight or more, relative to the weight of the oral care composition. 
     
     
         7 . The oral care composition of  claim 1 , wherein the oral care composition further comprises an abrasive. 
     
     
         8 . The oral care composition of  claim 1 , further comprising one or more humectants and/or one or more surfactants. 
     
     
         9 . The oral care composition of  claim 1 , further comprising an effective amount of one or more alkali phosphate salts. 
     
     
         10 . The oral care composition of  claim 1 , further comprising a whitening agent. 
     
     
         11 . The oral care composition of  claim 1 , further comprising one or more sources of zinc ions in addition to the zinc phosphate. 
     
     
         12 . The oral care composition of  claim 1 , wherein the oral care composition is a dentifrice, powder, cream, strip or gum. 
     
     
         13 . An oral care composition according to  claim 1 , which comprises:
 from 0.5 to 3% by weight zinc phosphate;   from 0.05 to 11% by weight stannous fluoride;   from 1 to 8% by weight alkali phosphate salts selected from sodium phosphate dibasic, potassium phosphate dibasic, dicalcium phosphate dihydrate, tetrasodium pyrophosphate, tetrapotassium pyrophosphate, calcium pyrophosphate, sodium tripolyphosphate, and mixtures of any two or more of these, relative to the weight of the oral care composition; and   a silica abrasive.   
     
     
         14 . The oral care composition of  claim 1 , wherein the oral care composition is a gel. 
     
     
         15 . The oral care composition of  claim 1 , wherein the pH of the composition is less than 7. 
     
     
         16 . A method of treating or reducing dental enamel erosion comprising administering a composition according to  claim 1  to the oral cavity of a subject in need thereof. 
     
     
         17 . The method of  claim 16 , wherein at least one tooth is remineralized after administration of said composition.