US2019209658A1PendingUtilityA1

Methods for treating an animal

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Assignee: PURETEIN BIOSCIENCE LLCPriority: Dec 19, 2013Filed: Mar 18, 2019Published: Jul 11, 2019
Est. expiryDec 19, 2033(~7.4 yrs left)· nominal 20-yr term from priority
A61P 31/12A61P 31/00A61K 9/0053A61K 38/30A61K 35/20A23K 20/147A61K 2035/124A61K 35/14Y02A40/70
36
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Claims

Abstract

Provided herein are methods for treating an animal using a composition that includes active IGF. The methods include treating an animal at risk of having an infection caused by an infectious agent, treating an animal having an infection, and treating a symptom associated with an infection. In one embodiment, the infectious agent is a virus. In one embodiment, the administering includes daily administration of at least 0.05 nanograms of active IGF-1 per kilogram bodyweight of the animal daily (ng/kg), at least 0.1 ng/kg, at least 2 ng/kg, at least 5 ng/kg, or at least 10 ng/kg.

Claims

exact text as granted — not AI-modified
1 . A method comprising:
 administering active IGF to an animal at risk of having an infection caused by an infectious agent, wherein the risk of having an infection is decreased compared to a control animal that is not administered the composition, wherein the infectious agent is human adenovirus, avian influenza, or swine influenza virus.   
     
     
         2 .- 78 . (canceled) 
     
     
         79 . The method of  claim 1  wherein the IGF is active IGF-1. 
     
     
         80 . The method of  claim 1  wherein the administering comprises oral administration of the active IGF. 
     
     
         81 . The method of  claim 80  wherein the oral administration comprises administration of a feed to the animal, wherein the feed comprises the active IGF. 
     
     
         82 . The method of  claim 1  wherein the administering comprises daily administration of at least 0.05 nanograms of active IGF-1 per kilogram bodyweight of the animal daily (ng/kg), at least 0.1 ng/kg, at least 2 ng/kg, at least 5 ng/kg, or at least 10 ng/kg. 
     
     
         83 . The method of  claim 1  wherein the IGF-1 administered to the subject is obtained from a natural source that has been processed to increase the amount of active IGF-1. 
     
     
         84 . The method of  claim 1  wherein the administering further comprises administering inactive IGF-1, wherein at least 20% of the total IGF-1 administered is active IGF-1. 
     
     
         85 . A method comprising:
 administering active IGF to an animal having an infection caused by an infectious agent, wherein the composition comprises active IGF-1, wherein the administering results in reducing the amount of infectious agent in the animal, wherein the infectious agent is human adenovirus, avian influenza, or swine influenza virus.   
     
     
         86 . The method of  claim 85  wherein the IGF is active IGF-1. 
     
     
         87 . The method of  claim 85  wherein the administering comprises oral administration of the active IGF. 
     
     
         88 . The method of  claim 87  wherein the oral administration comprises administration of a feed to the animal, wherein the feed comprises the active IGF. 
     
     
         89 . The method of  claim 85  wherein the administering comprises daily administration of at least 0.05 nanograms of active IGF-1 per kilogram bodyweight of the animal daily (ng/kg), at least 0.1 ng/kg, at least 2 ng/kg, at least 5 ng/kg, or at least 10 ng/kg. 
     
     
         90 . The method of  claim 85  wherein the IGF-1 administered to the subject is obtained from a natural source that has been processed to increase the amount of active IGF-1. 
     
     
         91 . The method of  claim 85  wherein the administering further comprises administering inactive IGF-1, wherein at least 20% of the total IGF-1 administered is active IGF-1. 
     
     
         92 . The method of  claim 90  wherein the natural source is blood or a blood-derived product. 
     
     
         93 . The method of  claim 90  wherein the natural source is milk or a milk-derived product. 
     
     
         94 . The method of  claim 90  wherein the natural source is colostrum or a colostrum-derived product.

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