Systems and Methods for Hypertension Control

Abstract

Systems and methods for hypertension control via energy delivery to one or more nerves affecting blood pressure are provided. Systems may include implantable devices configured for non-contacting neuromodulation. Implantable devices may be configured for intravascular implantation. Systems may also include external devices configured to communicated with implantable neuromodulation devices, Additional systems may include non-implantable devices for delivering modulation energy and ablation energy to one or more nerves affecting blood pressure.

1 .- 36 . (canceled) 
     
     
         37 . A device, comprising:
 a housing configured for location external to a body of a subject; and at least one processor associated with the housing and configured for electrical communication with a power source; and   an antenna associated with the at least one processor;   the at least one processor being configured to:   communicate with a circuit implanted in a subject's vasculature; and   adjust delivery of power from the power source to the implanted circuit based on a dynamic biological condition of the subject.   
     
     
         38 . The device of  claim 37 , further comprising a sensor associated with the at least one processor for detecting a subject's hypertension level. 
     
     
         39 . The device of  claim 37 , wherein the housing is configured to be worn by a subject and wherein the processor is configured to periodically adjusted delivery of power to the implanted circuit based on detected hypertension level. 
     
     
         40 . The device of  claim 37 , wherein the processor is further configured to receive therapy parameters, the therapy parameters including information about a subject's hypertension level. 
     
     
         41 . The device of  claim 37 , wherein the dynamic biological condition is associated with a hypertension level. 
     
     
         42 . The device of  claim 37 , wherein the dynamic biological condition is associated with Parkinson's Disease, tremors, depression, peripheral vascular disease, angina, claudication, diabetes, renal failure; and erectile dysfunction. 
     
     
         43 - 44 . (canceled) 
     
     
         45 . A device comprising:
 an intravascular delivery mechanism configured to deliver an intravascular implant to a location in at least one of a carotid artery and a jugular vein of a subject via at least one of an axillary artery and a jugular vein of the subject, the intravascular implant being removably secured to a distal end of the intravascular delivery mechanism;   the intravascular delivery mechanism comprising:   a carrier configured for intravascular delivery;   at least one electrode arranged for delivery with the carrier, the at least one electrode being configured and tuned to stimulate a glossopharyngeal nerve upon reception of a power signal sent from a location external to the subject's body; and   a circuit portion arranged for intravascular delivery with the carrier, the circuit portion being electrically connected to the at least one electrode.   
     
     
         46 . (canceled) 
     
     
         47 . A method of orienting an intravascular device, the method comprising:
 delivering the intravascular device to an implant location in vasculature of a subject's body, the intravascular device including a carrier and an antenna;   arranging an external antenna outside the body of the subject, the external antenna being electrically connected to a power source;   transmitting a wireless signal from the external antenna to the antenna of the intravascular device;   detecting a level of coupling between the external antenna and the antenna of the intravascular device;   adjusting a relative position of the intravascular device until a level of coupling exceeds a predetermined threshold; and   fixing the position of the intravascular device within the vasculature of the subject when the predetermined threshold is exceeded.   
     
     
         48 .- 62 . (canceled)