US2019248807A1PendingUtilityA1
Cot modulators and methods of use thereof
Est. expiryJul 6, 2035(~9 yrs left)· nominal 20-yr term from priority
Inventors:Elizabeth M. BaconGayatri BalanChienhung ChouChristopher T. ClarkJeromy J. CottellMusong KimThorsten A. KirschbergJohn O. LinkGary PhillipsScott D. SchroederNeil H. SquiresKirk L. StevensJames G. TaylorWilliam J. WatkinsNathan E. WrightSheila Zipfel
A61P 5/50A61P 7/00A61P 3/10A61P 9/06A61P 35/00A61P 37/02A61P 9/00A61P 7/06A61P 43/00A61P 3/00A61P 3/02A61P 31/04A61P 25/28A61P 27/02A61P 25/04A61P 29/00A61P 17/14A61P 25/00A61P 21/04A61P 1/06A61P 1/04A61P 19/06A61P 17/00A61P 21/02A61P 1/02A61P 13/12A61P 1/12A61P 1/08A61P 17/06A61P 1/00A61P 19/08A61P 19/02A61P 11/00A61P 11/06A61P 1/16C07D 471/04C07D 409/14C07D 413/14C07D 417/14C07D 495/04C07D 401/12C07B 59/002C07D 401/14C07D 498/04C07D 405/14C07B 2200/05A61K 31/4709C07D 215/44C07D 215/42A61P 37/00
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Claims
Abstract
The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof.
Claims
exact text as granted — not AI-modified1 . A compound of formula (A):
2 . A compound of formula (B):
3 . A method of preparing a compound of formula (A):
comprising the step of:
(a) contacting a compound of formula
with a compound of formula (B):
to form a mixture; and
b) combining the mixture with Pd(PPh 3 ) 2 Cl 2 under conditions sufficient to yield the compound of formula (A).Join the waitlist — get patent alerts
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