US2019269694A1PendingUtilityA1

Heterocyclic modulators of lipid synthesis

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Assignee: 3 V BIOSCIENCES INCPriority: Mar 8, 2011Filed: Oct 11, 2018Published: Sep 5, 2019
Est. expiryMar 8, 2031(~4.7 yrs left)· nominal 20-yr term from priority
C07D 401/14A61K 31/506A61K 31/5377C07D 401/06C07D 491/10A61K 31/501A61K 31/55C07D 471/04C07D 401/12A61K 31/437C07D 405/10A61K 31/4525A61K 31/496C07D 491/048A61K 31/4545C07D 491/107A61K 31/453C07D 405/04C07D 513/04C07D 405/14C07D 413/10C07D 401/10C07D 405/12C07D 401/04C07D 413/14A61K 31/451C07D 487/04A61K 31/454C07D 491/052
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Claims

Abstract

Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders, such as non-alcoholic steatohepatitis (NASH).

Claims

exact text as granted — not AI-modified
1 - 35 . (canceled) 
     
     
         36 . A pharmaceutical composition comprising a compound of the formula: 
       
         
           
           
               
               
           
         
       
       and a pharmaceutically acceptable carrier. 
     
     
         37 . A pharmaceutical composition comprising a compound of the formula: 
       
         
           
           
               
               
           
         
       
       and a pharmaceutically acceptable carrier. 
     
     
         38 . A pharmaceutical composition comprising a compound of the formula: 
       
         
           
           
               
               
           
         
       
       and a pharmaceutically acceptable carrier.

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