US2019321449A1PendingUtilityA1

Blood Plasma Fractions as a Treatment for Aging-Associated Cognitive Disorders

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Assignee: ALKAHEST INCPriority: Aug 18, 2016Filed: Jun 28, 2019Published: Oct 24, 2019
Est. expiryAug 18, 2036(~10.1 yrs left)· nominal 20-yr term from priority
Inventors:David BellIan GallagerSteven P. BraithwaiteS. Sakura MinamiVu Cao DangJoe MccrackenKaroly Nikolich
A61P 25/28A61K 35/16A61K 38/385A61K 38/38A61K 35/14
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Claims

Abstract

Methods and compositions for treating and/or preventing aging-related conditions are described. The compositions used in the methods include fractions derived from blood plasma with efficacy in treating and/or preventing aging-related conditions such as neurocognitive disorders.

Claims

exact text as granted — not AI-modified
What is claimed: 
     
         1 . A method of treating a cognitive disorder, comprising administering an effective amount of a Plasma Fraction to a subject diagnosed with a cognitive disorder. 
     
     
         2 . The method of  claim 1  wherein the Plasma Fraction is a Plasma Protein Fraction. 
     
     
         3 . The method of  claim 2  wherein the Plasma Protein Fraction is a commercially available Plasma Protein Fraction. 
     
     
         4 . The method of  claim 1  wherein the Plasma Fraction is a Human Albumin Solution. 
     
     
         5 . The method of  claim 4  wherein the Human Albumin Solution is a commercially available Human Albumin Solution. 
     
     
         6 . The method of  claim 1  wherein the Plasma Fraction is a protein-enriched plasma protein product. 
     
     
         7 . The method of  claim 1  wherein the Plasma Fraction is Effluent I. 
     
     
         8 . The method of  claim 1  wherein the Plasma Fraction is Effluent II/III. 
     
     
         9 . The method of  claim 1  further comprising monitoring the subject for improved cognitive function. 
     
     
         10 . The method of  claim 1  wherein the Plasma Fraction is derived from plasma from a pool of young individuals. 
     
     
         11 . The method of  claim 1  wherein the Plasma Fraction is produced from a mammalian blood product. 
     
     
         12 . The method of  claim 11  wherein the mammalian blood product is a human blood product. 
     
     
         13 . The method of  claim 1  wherein the subject is a mammal. 
     
     
         14 . The method of  claim 13  wherein the mammal is a human. 
     
     
         15 . A kit for use in treating a subject for a cognitive disorder, the kit comprising a containing comprising a Plasma Fraction as described in  claim 1 .

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