US2019374573A1PendingUtilityA1
Botanical film-forming acne compositions
Est. expiryJun 12, 2038(~11.9 yrs left)· nominal 20-yr term from priority
A61K 47/12A61K 31/722A61K 36/899A61K 31/352A61K 31/315A61P 31/02A61K 36/61A61P 17/08A61P 17/04A61K 36/484A61K 36/48A61K 36/53A61K 36/28A61K 47/10A61K 31/194A61K 31/60A61K 47/38A61K 31/19A61K 36/74A61K 36/82A61K 36/752A61K 31/05A61K 33/30A61P 17/10A61K 36/896A61K 36/81A61P 17/00A61K 36/324A61K 36/185A61K 36/886A61K 47/20A61P 31/04A61K 9/0014A61K 9/107A61K 9/06A61K 31/327A61K 31/192A61K 31/045
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Claims
Abstract
The present technology relates to botanical film-forming compositions useful for the treatment of acne related skin disorders, as well as methods of treating such disorders. The compositions herein are advantageous in that they treat acne related skin disorders quickly and with minimal irritation and side effects.
Claims
exact text as granted — not AI-modifiedWe claim:
1 . A composition suitable for treating an acne related skin disorder, comprising:
(a) 0.1 to 1% w/w hydroxypropyl methylcellulose stearoxy ether (hydrophobically modified hydroxypropyl methylcellulose) (HPMCSE polymer); (b) 0.1 to 1% w/w soluble zinc salt, wherein the soluble zinc salt is zinc gluconate, zinc lactate, zinc acetate, zinc citrate or any combination thereof; (c) 0.1 to 5% w/w emulsifying agent, wherein the emulsifying agent comprises: (1) 0.1 to 5% w/w of one more of: behentrimonium methosulfate, cetyl alcohol, stearyl alcohol, butylene glycol, or a cetyl alcohol and butylene glycol blend (referred to as BTMSCB) or any combination thereof; and (2) 0.1 to 5% w/w nonionic self-emulsifying wax; and (d) 0.5 to 2% w/w salicylic acid, or 0.5 to 10% w/w benzoyl peroxide, or a combination thereof.
2 . The composition of claim 1 , further comprising 0.1 to 1% w/w chitosan.
3 . The composition of claim 1 , further comprising 0.1 to 3% cellulose polymer, wherein the cellulose polymer is hydroxyethyl cellulose, hydroxyl propyl methyl cellulose, methyl cellulose, polyquaternium 10, or any combination thereof.
4 . The composition of claim 1 , further comprising 0.1 to 2% calendula oil or extract, or 0.1 to 5% aloe gel or extract, or any combination thereof.
5 . The composition of claim 1 , further comprising 0.5 to 10% w/w emollient solvent, wherein the emollient solvent is 1,3-propanediol, glycerin, caprylil capryl triglyceride, butylene glycol, octanediol, decanediol, benzyl alcohol, ethyl hexyl glycerin, farnesol or any combination thereof.
6 . The composition of claim 1 , further comprising a botanical, wherein the botanical is orange oil, 0.05 to 0.2% w/w rosemary oil, 0.01 to 0.1% w/w vetiver oil, 0.01 to 0.1% w/w red sandalwood paste or extract, 0.2 to 1% w/w pomegranate oil or extract, 0.3 to 1% w/w grapefruit seed extract; 0.3 to 1% w/w lemon extract, 0.2 to 3% tea tree oil, 0.2 to 2% w/w arnica oil, 0.2 to 2% w/w licorice extract, 0.2 to 2% frankincense oil, 0.01 to 2% w/w helichrysum oil, 0.01 to 1% w/w Withania somnifera flower extract, 0.01 to 1% w/w manjistha ( Rubia cordifolia ) extract, or any combination thereof.
7 . The composition of claim 1 , further comprising 0.1 to 1% each of glycolic acid, lactic acid, benzoic acid or a combination thereof.
8 . The composition of claim 1 , further comprising 0.5 to 15% of an additional ingredient, wherein the additional ingredient is one or more of the following: a solvent or solubilizing agent; a surfactant water, alcohol, sorbitan mono laurate, sorbitan mono oleate, sorbitan oleate decylglucoside, sorbitan sugar, caprylil capryl glucoside, mixture of PEG 40 hydrogenated castor oil, trideceth-9 propylene glycol, cocoamidopropyl betaine, water or any combination thereof.
9 . The composition of claim 1 , further comprising an essential oil or constituent thereof, or a botanical extract; wherein the essential oil or constituent thereof or botanical extract is lavender oil, chamomile oil, basil oil, thyme oil, thymol, menthol, orange oil, vetiver oil, bakuchiol, jojoba oil, white tea extract, green tea extract, witch hazel extract, bisabolol, resveratrol or any combination thereof.
10 . The composition of claim 1 , further comprising 0.1 to 1% preservative, wherein the preservative is chlorhexidine, benzalkonium chloride, phenoxyethanol, phenyl ethanol or any combination thereof.
11 . The composition of claim 1 , further comprising 0.1 to 1% antioxidant, wherein the antioxidant is Vitamin E, Vitamin C or any combination thereof.
12 . A method of treating an acne related skin disorder, comprising contacting the composition of claim 1 with the skin.
13 . A method of treating an acne related skin disorder, comprising the following steps:
(a) dissolving soluble zinc salt, aloe powder, lactic acid and glycolic acid in water at a temperature of 50 to 60° C.; (b) optionally adding a thickener or surfactant; (c) adding an emulsifying agent, the emulsifying agent comprising behentrimonium methosulfate, cetyl alcohol and butylene glycol (BTMSCB) and nonionic self-emulsifying wax; and mixing until dissolved; (d) allowing the mixture to cool down to 30 to 40° C.; (e) adding HPMCSE polymer gel, chitosan gel and calendula extract; (f) mixing to obtain a creamy gel (Phase A); (g) combining salicylic acid and one or more botanical extracts or oils in a solvent, and mixing (Phase B); (h) combining Phase A and B to obtain an acne composition; and (i) contacting the acne composition with skin.Join the waitlist — get patent alerts
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