US2020013133A1PendingUtilityA1

Computing system and method for determining safety index of product

Assignee: VITARGENT INTERNATIONAL BIOTECHNOLOGY LTDPriority: Jul 9, 2018Filed: Jul 9, 2019Published: Jan 9, 2020
Est. expiryJul 9, 2038(~11.9 yrs left)· nominal 20-yr term from priority
G01N 33/5014G16C 20/30G06Q 30/018G06F 17/11G06Q 50/265G06Q 30/0282G16C 20/00
39
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Claims

Abstract

The present invention relates to computing system and method for determining a safety index of a product. The method includes: retrieving, by the computing system, a plurality of toxicity values of the product from a toxicity database, wherein the toxicity values correspond to a plurality types of the product respectively; retrieving, by the computing system, a plurality of weight values of the product from a weight database, wherein the weight values correspond to the types of the product respectively; and determining, by the computing system, the safety index of the product according to the toxicity values and the weight values.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A method for determining a safety index of a product, the method comprising:
 retrieving, by a computing system, a plurality of toxicity values of the product from a toxicity database, wherein the toxicity values correspond to a plurality types of the product respectively;   retrieving, by the computing system, a plurality of weight values of the product from a weight database, wherein the weight values correspond to the types of the product respectively; and   determining, by the computing system, the safety index of the product according to the toxicity values and the weight values.   
     
     
         2 . The method of  claim 1 , wherein a toxicity test is optionally performed to a plurality of samples of the types of the product to obtain the toxicity values, and the method further comprises:
 storing, by the computing system, the toxicity values in the toxicity database.   
     
     
         3 . The method of  claim 2 , wherein the toxicity test includes an acute toxicity test and the toxicity values are associated with lethal concentration 50% (LC 50 ) values. 
     
     
         4 . The method of  claim 2 , wherein the toxicity test includes a chronic toxicity test and the toxicity values are associated with estradiol equivalent concentration (EEQ) values. 
     
     
         5 . The method of  claim 1 , wherein the weight values include sales volume information. 
     
     
         6 . The method of  claim 1 , wherein the safety index of the product is determined based on following formula: 
       
         
           
             
               SI 
               = 
               
                 
                   ∑ 
                   
                     h 
                     = 
                     1 
                   
                   x 
                 
                  
                 
                   
                     
                       T 
                       _ 
                     
                     h 
                   
                   × 
                   
                     ω 
                     h 
                   
                 
               
             
           
         
         wherein SI represents the safety index of the product, x represents number of the types of the product,  T   h  represents the toxicity value of h th  type of the product, and ω h  represents the weight value of h th  type of the product. 
       
     
     
         7 . The method of  claim 6 , wherein  T   h  is determined based on following formula: 
       
         
           
             
               
                 
                   T 
                   _ 
                 
                 h 
               
               = 
               
                 
                   1 
                   
                     N 
                     h 
                   
                 
                  
                 
                   
                     ∑ 
                     
                       i 
                       = 
                       1 
                     
                     
                       N 
                       h 
                     
                   
                    
                   
                     T 
                     hi 
                   
                 
               
             
           
         
         wherein N h  represents number of samples of h th  type of the product and T hi  represents a toxicity test value of i th  sample of h th  type of the product. 
       
     
     
         8 . The method of  claim 7 , wherein  T   h  is transformed to  T   H  based on following formulas: 
       
         
           
             
               
                 T 
                 hi 
                 * 
               
               = 
               
                 
                   
                     
                       T 
                       hi 
                     
                     - 
                     
                       
                         
                           min 
                            
                           
                               
                           
                         
                         
                           1 
                           ≤ 
                           i 
                           ≤ 
                           
                             N 
                             h 
                           
                         
                       
                        
                       
                         T 
                         hi 
                       
                     
                   
                   
                     
                       
                         
                           max 
                            
                           
                               
                           
                         
                         
                           1 
                           ≤ 
                           i 
                           ≤ 
                           
                             N 
                             h 
                           
                         
                       
                        
                       
                         T 
                         hi 
                       
                     
                     - 
                     
                       
                         mix 
                         
                           1 
                           ≤ 
                           i 
                           ≤ 
                           
                             N 
                             h 
                           
                         
                       
                        
                       
                           
                       
                        
                       
                         T 
                         hi 
                       
                     
                   
                 
                 × 
                 100 
                  
                 % 
               
             
           
         
         
           
             
               
                 
                   T 
                   _ 
                 
                 H 
               
               = 
               
                 
                   1 
                   
                     N 
                     h 
                   
                 
                  
                 
                   
                     ∑ 
                     
                       i 
                       = 
                       1 
                     
                     
                       N 
                       h 
                     
                   
                    
                   
                     T 
                     hi 
                     * 
                   
                 
               
             
           
         
       
     
     
         9 . The method of  claim 6 , wherein (oh is determined based on following formula: 
       
         
           
             
               
                 ω 
                 h 
               
               = 
               
                 
                   
                     ∑ 
                     
                       i 
                       = 
                       1 
                     
                     
                       N 
                       h 
                     
                   
                    
                   
                     
                       C 
                       hi 
                     
                      
                     
                       P 
                       hi 
                     
                   
                 
                 
                   
                     ∑ 
                     
                       h 
                       = 
                       1 
                     
                     x 
                   
                    
                   
                     
                       ∑ 
                       
                         i 
                         = 
                         1 
                       
                       
                         N 
                         h 
                       
                     
                      
                     
                       
                         C 
                         hi 
                       
                        
                       
                         P 
                         hi 
                       
                     
                   
                 
               
             
           
         
         wherein N h  represents number of samples of h th  type of the product, C hi  represents an amount of i th  sample of h th  type of the product and P hi  represents a rank weight of i th  sample of h th  type of the product. 
       
     
     
         10 . The method of  claim 9 , wherein the rank weights are based on product popularities which reflect the sales volume information to a certain extent. 
     
     
         11 . A computing system for determining a safety index of a product, the computing system comprising:
 a processor; and   a memory storing instructions that, when being executed, cause the processor to:
 retrieve a plurality of toxicity values of the product from a toxicity database, wherein the toxicity values correspond to a plurality types of the product respectively; 
 retrieve a plurality of weight values of the product from a weight database, wherein the weight values correspond to the types of the product respectively; and 
 determine the safety index of the product according to the toxicity values and the weight values. 
   
     
     
         12 . The computing system of  claim 11 , wherein a toxicity test is optionally performed to a plurality of samples of the types of the product to obtain the toxicity values, and the instructions, when being executed, further cause the processor to:
 store the toxicity values in the toxicity database.   
     
     
         13 . The computing system of  claim 12 , wherein the toxicity test includes an acute toxicity test and the toxicity values are associated with lethal concentration 50% (LC 50 ) values. 
     
     
         14 . The computing system of  claim 12 , wherein the toxicity test includes a chronic toxicity test and the toxicity values are associated with estradiol equivalent concentration (EEQ) values. 
     
     
         15 . The computing system of  claim 11 , wherein the weight values include sales volume information. 
     
     
         16 . The computing system of  claim 11 , wherein the safety index of the product is determined based on following formula: 
       
         
           
             
               SI 
               = 
               
                 
                   ∑ 
                   
                     h 
                     = 
                     1 
                   
                   x 
                 
                  
                 
                   
                     
                       T 
                       _ 
                     
                     h 
                   
                   × 
                   
                     ω 
                     h 
                   
                 
               
             
           
         
         wherein SI represents the safety index of the product, x represents number of the types of the product,  T   h  represents the toxicity value of h th  type of the product, and ω h  represents the weight value of h th  type of the product. 
       
     
     
         17 . The computing system of  claim 16 , wherein  T   h  is determined based on following formula: 
       
         
           
             
               
                 
                   T 
                   _ 
                 
                 h 
               
               = 
               
                 
                   1 
                   
                     N 
                     h 
                   
                 
                  
                 
                   
                     ∑ 
                     
                       i 
                       = 
                       1 
                     
                     
                       N 
                       h 
                     
                   
                    
                   
                     T 
                     hi 
                   
                 
               
             
           
         
         wherein N h  represents number of samples of h th  type of the product and T hi  represents a toxicity test value of i th  sample of h th  type of the product. 
       
     
     
         18 . The computing system of  claim 17 , wherein  T   h  is transformed to  T   H  based on following formulas: 
       
         
           
             
               
                 T 
                 hi 
                 * 
               
               = 
               
                 
                   
                     
                       T 
                       hi 
                     
                     - 
                     
                       
                         
                           min 
                            
                           
                               
                           
                         
                         
                           1 
                           ≤ 
                           i 
                           ≤ 
                           
                             N 
                             h 
                           
                         
                       
                        
                       
                         T 
                         hi 
                       
                     
                   
                   
                     
                       
                         
                           max 
                            
                           
                               
                           
                         
                         
                           1 
                           ≤ 
                           i 
                           ≤ 
                           
                             N 
                             h 
                           
                         
                       
                        
                       
                         T 
                         hi 
                       
                     
                     - 
                     
                       
                         mix 
                         
                           1 
                           ≤ 
                           i 
                           ≤ 
                           
                             N 
                             h 
                           
                         
                       
                        
                       
                           
                       
                        
                       
                         T 
                         hi 
                       
                     
                   
                 
                 × 
                 100 
                  
                 % 
               
             
           
         
         
           
             
               
                 
                   T 
                   _ 
                 
                 H 
               
               = 
               
                 
                   1 
                   
                     N 
                     h 
                   
                 
                  
                 
                   
                     ∑ 
                     
                       i 
                       = 
                       1 
                     
                     
                       N 
                       h 
                     
                   
                    
                   
                     T 
                     hi 
                     * 
                   
                 
               
             
           
         
       
     
     
         19 . The computing system of  claim 16 , wherein Wh is determined based on following formula: 
       
         
           
             
               
                 ω 
                 h 
               
               = 
               
                 
                   
                     ∑ 
                     
                       i 
                       = 
                       1 
                     
                     
                       N 
                       h 
                     
                   
                    
                   
                     
                       C 
                       hi 
                     
                      
                     
                       P 
                       hi 
                     
                   
                 
                 
                   
                     ∑ 
                     
                       h 
                       = 
                       1 
                     
                     x 
                   
                    
                   
                     
                       ∑ 
                       
                         i 
                         = 
                         1 
                       
                       
                         N 
                         h 
                       
                     
                      
                     
                       
                         C 
                         hi 
                       
                        
                       
                         P 
                         hi 
                       
                     
                   
                 
               
             
           
         
         wherein N h  represents number of samples of h th  type of the product, C hi  represents an amount of i th  sample of h th  type of the product and P hi  represents a rank weight of i th  sample of h th  type of the product. 
       
     
     
         20 . The computing system of  claim 19 , wherein the rank weights are based on the product popularities which reflect the sales volume information to a certain extent.

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