US2020030398A1PendingUtilityA1

Skin care composition

Assignee: ISN PHARMA SP Z O OPriority: Nov 12, 2015Filed: Oct 8, 2019Published: Jan 30, 2020
Est. expiryNov 12, 2035(~9.3 yrs left)· nominal 20-yr term from priority
Inventors:Sylwia Nowak
A61Q 19/007A61Q 19/00A61K 8/9794A61K 36/41A61P 37/00A61K 47/14A61K 8/342A61K 47/10A61K 2800/87A61K 47/44A61K 8/927A61K 9/06A61P 17/06A61K 47/22A61K 8/4946A61K 9/0014A61K 8/9789A61K 9/7023A61K 8/97A61K 36/185A61K 36/3482
45
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Claims

Abstract

The present invention relates to methods of skin care or treating dermal conditions characterized by itching, skin redness, skin roughness, keratosis and squama, the method comprising: applying a composition for topical administration comprising a therapeutically effective amount of Kalanchoe daigremontiana extract or juice to an affected area. The compositions are therapeutically effective for hydrating and conditioning the skin and are shown to be clinically effective at treating dermal conditions or skin disorders, in particular, psoriasis, atopic dermatitis or allergic contact dermatitis.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A method of skin care or treating a dermal condition characterized by a combination of at least two symptoms selected from increased itching, skin redness, skin roughness, keratosis and squama, the method comprising:
 applying a composition for topical administration comprising a therapeutically effective amount of  Kalanchoe daigremontiana  extract or juice to an affected area.   
     
     
         2 . The method of skin care or treating a dermal condition of  claim 1  wherein the composition for topical administration further comprises at least one excipient for use in the treatment or prevention of a dermal condition. 
     
     
         3 . The method of skin care or treating a dermal condition of  claim 2  wherein the dermal condition is selected from the group consisting of atopic dermatitis, allergic contact dermatitis, and psoriasis. 
     
     
         4 . The method of skin care or treating a dermal condition of  claim 1  wherein the dermal condition is selected from the group consisting of atopic dermatitis, allergic contact dermatitis, and psoriasis 
     
     
         5 . The method of skin care or treating a dermal condition of  claim 1  wherein the composition for topical administration comprises 1-30% w/w of  Kalanchoe daigremontiana  extract or juice. 
     
     
         6 . The method of skin care or treating a dermal condition of  claim 5  wherein the composition for topical administration comprises 4-20% w/w glycerol monostearate. 
     
     
         7 . The method of skin care or treating a dermal condition of  claim 6  wherein the composition for topical administration comprises 35-75% w/w demineralized water. 
     
     
         8 . The method of skin care or treating a dermal condition of  claim 7  wherein the composition for topical administration further comprises one or more of beeswax, coconut oil, cetyl alcohol, shea butter, and  Cannabis sativa  (Hemp) Seed Oil. 
     
     
         9 . A method for making a topical composition, the method comprising:
 heating a solution of water;   heating fat(s) comprising glycerol monostearate and stirring until smooth;   combining the fat(s) and the solution;   heating the combined fat and solution;   stirring the combined fat and solution until a smooth and homogenous product is obtained;   cooling the stirred, combined fat and solution; and   adding a therapeutically effective amount of  Kalanchoe daigremontiana  extract or juice to the resulting mixture.   
     
     
         10 . The method for making a topical composition of  claim 9  wherein the water is demineralized water. 
     
     
         11 . The method of  claim 10 , wherein the solution comprises 35-75% w/w demineralized water. 
     
     
         12 . The method for making a topical composition of  claim 10  wherein the solution of demineralized water is heated at 30 to 75 degrees C. 
     
     
         13 . The method of  claim 9 , wherein 1-30% w/w of  Kalanchoe daigremontiana  extract or juice is added to the resulting mixture. 
     
     
         14 . The method of  claim 9 , wherein the fat(s) comprises 4-20% w/w glycerol monostearate. 
     
     
         15 . The method of  claim 9  wherein the fat comprises 6-65% w/w glycerol monostearate and one or more of beeswax, coconut oil, cetyl alcohol, shea butter, and  Cannabis sativa  (Hemp) Seed Oil. 
     
     
         16 . The method of  claim 9  wherein the fat comprises 4-28% w/w of beeswax, and/or 4-40% w/w of coconut oil, and/or 2-25% w/w of cetyl alcohol, and/or 2-10% w/w of shea butter. 
     
     
         17 . The method of  claim 9 , wherein the mixture of fats is heated up to 30-75 degrees C. 
     
     
         18 . The method of  claim 9 , wherein allantoin is added to the heated solution. 
     
     
         19 . The method of making a transdermal patch comprising: making a topical composition in accordance with the method of  claim 9  and applying the composition into or onto a patch suitable for delivering the composition to skin. 
     
     
         20 . A method of skin care or treating a dermal condition characterized by a combination of at least two symptoms selected from increased itching, skin redness, skin roughness, keratosis and squama, the method comprising:
 preparing a composition for topical administration comprising a therapeutically effective amount of  Kalanchoe daigremontiana , the preparation comprising:   heating a solution of water;   heating fat(s) comprising glycerol monostearate and stirring until smooth;   combining the fat(s) and the solution;   heating the combined fat and solution;   stirring the combined fat and solution until a smooth and homogenous product is obtained;   cooling the stirred, combined fat and solution; and   adding a therapeutically effective amount of  Kalanchoe daigremontiana  extract or juice to the resulting mixture; and   applying the composition for topical administration comprising a therapeutically effective amount of  Kalanchoe daigremontiana  extract or juice to an affected area,   wherein the water is demineralized water,   wherein the solution comprises 35-75% w/w demineralized water,   wherein the solution of demineralized water is heated at 30 to 75 degrees C.,   wherein 1-30% w/w of  Kalanchoe daigremontiana  extract or juice is added to the resulting mixture,   wherein the fat comprises 6-65% w/w glycerol monostearate and one or more of beeswax, coconut oil, cetyl alcohol, shea butter, and  Cannabis sativa  (Hemp) Seed Oil,   wherein the mixture of fats is heated up to 30-75 degrees C., and   wherein allantoin is added to the heated solution.

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