US2020054757A1PendingUtilityA1

Cyclosporin compositions

Assignee: SAINT REGIS MOHAWK TRIBEPriority: Jul 13, 2005Filed: Oct 28, 2019Published: Feb 20, 2020
Est. expiryJul 13, 2025(expired)· nominal 20-yr term from priority
A61P 27/02A61K 38/13A61K 9/0048A61K 9/107A61K 47/44Y10S514/975Y10S514/912
65
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Claims

Abstract

A composition comprising from about 0.001% to about 0.4% cyclosporin A, a surfactant, and an oil having a specific gravity from 0.8 to 0.95 is disclosed herein.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A method of treating keratoconjunctivis sicca, the method comprising administering a composition comprising from about 0.001% to about 0.4% cyclosporin A, a surfactant, and an oil having a specific gravity from 0.8 to 0.95 to a patient in need thereof, wherein said composition is an ophthalmically acceptable emulsion. 
     
     
         2 . The method of  claim 1  wherein said oil has a specific gravity of from 0.90 to 0.95. 
     
     
         3 . The method of  claim 1  comprising from about 0.005% to about 0.05% cyclosporin A. 
     
     
         4 . The method of  claim 3  comprising about 0.05% cyclosporin A. 
     
     
         5 . The method of  claim 4  comprising almond oil. 
     
     
         6 . The method of  claim 4  comprising corn oil. 
     
     
         7 . The method of  claim 4  comprising arachis oil. 
     
     
         8 . The method of  claim 4  comprising cottonseed oil. 
     
     
         9 . The method of  claim 4  comprising safflower oil. 
     
     
         10 . The method of  claim 4  comprising maize oil. 
     
     
         11 . The method of  claim 4  comprising linseed oil. 
     
     
         12 . The method of  claim 4  comprising rapeseed oil. 
     
     
         13 . The method of  claim 4  comprising soybean oil. 
     
     
         14 . The method of  claim 4  comprising olive oil. 
     
     
         15 . The method of  claim 4  comprising caraway oil. 
     
     
         16 . The method of  claim 4  comprising rosemary oil. 
     
     
         17 . The method of  claim 4  comprising peanut oil. 
     
     
         18 . The method of  claim 4  comprising peppermint oil. 
     
     
         19 . The method of  claim 4  comprising sunflower oil. 
     
     
         20 . The method of  claim 4  comprising eucalpytus oil.

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