US2020078353A1PendingUtilityA1
Oligomer-opioid agonist conjugates
Est. expiryMar 12, 2027(~0.6 yrs left)· nominal 20-yr term from priority
C07D 489/02A61K 31/402A61K 47/60A61K 31/485A61K 31/439A61K 31/4025A61K 47/10A61K 31/4468C07D 489/08
63
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Claims
Abstract
The invention provides compounds that are chemically modified by covalent attachment of a water-soluble oligomer. A compound of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from those of the compound not attached to the water-soluble oligomer.
Claims
exact text as granted — not AI-modifiedWhat is claimed is:
1 . A compound having the formula:
wherein n is an integer having a value of from 1 to 9, and pharmaceutically acceptable salts thereof.
2 . The compound of claim 1 , wherein n is 1.
3 . The compound of claim 1 , wherein n is 2.
4 . The compound of claim 1 , wherein n is 3.
5 . The compound of claim 1 , wherein n is 4.
6 . The compound of claim 1 , wherein n is 5.
7 . The compound of claim 1 , wherein n is 6.
8 . The compound of claim 1 , wherein n is 7.
9 . The compound of claim 1 , wherein n is 8.
10 . The compound of claim 1 , wherein n is 9.
11 . A compound having the formula:
wherein n is an integer having a value of from 1 to 9, and pharmaceutically acceptable salts thereof.
12 . The compound of claim 11 , wherein n is 1.
13 . The compound of claim 11 , wherein n is 2.
14 . The compound of claim 11 , wherein n is 3.
15 . The compound of claim 11 , wherein n is 4.
16 . The compound of claim 11 , wherein n is 5.
17 . The compound of claim 11 , wherein n is 6.
18 . The compound of claim 11 , wherein n is 7.
19 . The compound of claim 11 , wherein n is 8.
20 . The compound of claim 11 , wherein n is 9.Join the waitlist — get patent alerts
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