US2020079845A1PendingUtilityA1

Compounds

Assignee: MEDIMMUNE LTDPriority: Nov 30, 2006Filed: Mar 21, 2019Published: Mar 12, 2020
Est. expiryNov 30, 2026(~0.4 yrs left)· nominal 20-yr term from priority
A61P 9/10A61P 3/10A61P 43/00A61P 7/06A61P 5/14A61P 7/08A61P 37/02A61P 37/06A61P 37/00A61P 3/04A61P 33/00A61P 35/02A61P 27/00A61P 31/12A61P 31/10A61P 35/00A61P 25/00A61P 31/04A61P 29/00A61P 31/16A61P 33/06A61P 31/18A61P 31/00A61P 21/00A61P 19/06A61P 19/02A61P 19/00A61P 17/14A61P 17/06A61P 17/04A61P 17/00A61P 15/00A61P 13/12A61P 11/06A61P 11/00A61P 1/16A61P 1/04A61P 1/00C07K 2317/52C07K 2317/92C07K 16/248C07K 2317/515A61K 2039/505C07K 2317/76G01N 33/6857C07K 2317/567C07K 2317/56C07K 2317/565C07K 2317/51C07K 2317/622C07K 2317/34C07K 2317/73C07K 2317/21G01N 2333/5412C07K 16/24C12N 15/11A61K 39/395
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Claims

Abstract

Binding members, e.g. human antibody molecules, which bind interleukin-6 (IL-6) and neutralise its biological effects. Use of binding members for IL-6 in medical treatment e.g. for treating inflammatory diseases and tumours associated with IL-6.

Claims

exact text as granted — not AI-modified
1 . An isolated binding member for human IL-6, which binds human IL-6 with a KD of not more than 30 pM as defined by surface plasmon resonance. 
     
     
         2 .- 73 . (canceled)

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