US2020093834A1PendingUtilityA1

Compositions for delivering a bio-active agent or bio-active agents

65
Assignee: SHEETRIT EYALPriority: Nov 25, 2014Filed: Aug 5, 2019Published: Mar 26, 2020
Est. expiryNov 25, 2034(~8.4 yrs left)· nominal 20-yr term from priority
Inventors:Eyal SheetritIzhar HalahmiIshay Attar
A61K 47/32A61K 47/34A61P 43/00A61K 9/0051A61K 47/02A61K 31/5377A61K 2300/00A61K 31/5575A61P 27/06
65
PatentIndex Score
0
Cited by
0
References
0
Claims

Abstract

In some embodiments, the present invention is a composition, including: a bulking agent, where the bulking agent is a kaolin, an absorbent material, where the absorbent material is a fumed silica, a binder, where the binder is an epoxy, and a first active agent, where the first active agent is Latanoprost.

Claims

exact text as granted — not AI-modified
1 . A composition, comprising:
 a bulking agent comprising a kaolin,   an absorbent material comprising a fumed silica,   a binder comprising an epoxy, and   a first active agent comprising Latanoprost
 wherein the bulking agent, the absorbent material, the binder, and 
 the first active agent are present in a composite; and 
   wherein the composition is in the form of a punctal plug.   
     
     
         2 . The composition of  claim 1 , wherein the first active agent is present in an amount of 5-40% by weight (w/w) of the composition. 
     
     
         3 . The composition of  claim 1 , further comprising a second active agent, wherein the second active agent comprises Timolol. 
     
     
         4 . The composition of  claim 3 , wherein the Timolol is present in an amount of 5-40% by weight (w/w) of the composition. 
     
     
         5 . The composition of  claim 1 , wherein the composition further comprises polyurethane. 
     
     
         6 . The composition of  claim 1 , wherein the composition further comprises a parylene coating. 
     
     
         7 . The composition of  claim 6 , wherein a thickness of the parylene coating ranges from 2-5 micrometers. 
     
     
         8 . The composition of  claim 1 , wherein the composition further comprises a butvar coating. 
     
     
         9 . The composition of  claim 8 , wherein a thickness of the butvar coating ranges from 2-5 micrometers. 
     
     
         10 .- 20 . (canceled) 
     
     
         21 . The composition of  claim 1 , wherein the composition is configured to release from 0.5-10 micrograms of the first active agent per day to an eye of a mammal in need thereof.

Cited by (0)

No later patents cite this yet.

References (0)

No backward citations on record.