US2020102564A1PendingUtilityA1

Use of Telomerase Inhibitors for the Treatment of Myeloproliferative Disorders and Myeloproliferative Neoplasms

Assignee: GERON CORPPriority: Dec 7, 2012Filed: Sep 25, 2018Published: Apr 2, 2020
Est. expiryDec 7, 2032(~6.4 yrs left)· nominal 20-yr term from priority
B82Y 5/00A61K 47/543A61K 49/0423A61K 47/549C12N 2320/30C12N 15/1135
60
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Claims

Abstract

Provided herein are methods for reducing neoplastic progenitor cell proliferation and alleviating symptoms associated in individuals diagnosed with or thought to have Essential Thrombocythemia (ET). Also provided herein are methods for using telomerase inhibitors for maintaining blood platelet counts at relatively normal ranges in the blood of individuals diagnosed with or suspected of having ET.

Claims

exact text as granted — not AI-modified
1 . A method for alleviating at least one symptom associated with myeloproliferative neoplasms or myelodysplastic syndrome in an individual in need thereof, the method comprising:
 administering a clinically effective amount of a telomerase inhibitor to the individual, wherein administration of the telomerase inhibitor alleviates at least one symptom associated with myeloproliferative neoplasms or myelodysplastic syndrome.   
     
     
         2 .- 41 . (canceled)

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