US2020129599A1PendingUtilityA1

Crystallized oxalate decarboxylase and methods of use

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Assignee: ALLENA PHARMACEUTICALS INCPriority: Aug 2, 2006Filed: Jun 19, 2019Published: Apr 30, 2020
Est. expiryAug 2, 2026(~0.1 yrs left)· nominal 20-yr term from priority
Inventors:Bhami ShenoyTeresa G. CacheroJohn ShinLekai ZhangAftab RashidDanica GrujicReena J. PatelMargaret Mcgrath
G01N 2333/988A61P 1/14A61P 7/08A61K 38/51A61K 38/00A61M 2202/0413A61K 9/0034A61P 13/02A61P 9/00A61P 9/10C12Q 1/527A61P 7/00A61P 29/00A61P 13/12A61P 1/04C07K 2299/00A61P 13/04A61P 19/00A61P 43/00C12Y 401/01002A61P 15/00A61P 1/18A61P 1/12C12N 9/88A61M 2205/75A61P 13/00A61P 1/16A61P 1/00A61M 1/16A61M 1/3687
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Claims

Abstract

Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using oxalate decarboxylase crystals are also disclosed. Additionally disclosed are methods of producing protein crystals.

Claims

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1 . A pharmaceutical composition comprising an oxalate decarboxylase crystal. 
     
     
         2 .- 33 . (canceled)

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