Har-nds-derived stem cells, method for separating same, and use thereof

Abstract

The present invention relates to hyaluronic acid-rich node and duct system (HAR-NDS)-derived stem cells, a method for separating the same, and a use thereof and, more specifically, to node and ductal stem cells (NDSCs), which are adult stem cells having an ability to differentiate into HAR-NDS-derived neural cells, and hematopoietic stem cells having an ability to differentiate into blood cells. The present invention is capable of separating, from HAR-NDS, adult stem cells NDSCs and hematopoietic stem cells, which are not easy to obtain from bone marrow, peripheral blood and umbilical cord blood (cord blood), as an alternative source, and thus can be usefully used for treatment of brain diseases, neurological diseases, chronic infectious diseases, cancers, autoimmune diseases, organ regeneration treatments and various intractable diseases.

1 - 42 . (canceled) 
     
     
         43 . Mammal-derived hyaluronic acid-rich node and duct system (HAR-NDS)-derived adult stem cells (NDSCs), which have the following characteristics:
 (a) a potential for differentiation into neuronal cells;   (b) an immunological characteristic of a very small embryonic-like stem cell (VSEL), which is selected from the group consisting of Sca-1 + , Lin − , and CD45 − ; and   (c) an immunological characteristic of an embryonic stem cell, which is selected from the group consisting of Oct4 + , Sox2 + , Nanog + , and SSEA-1 + .