US2020155628A1PendingUtilityA1

Plant extract from low-thc cannabis for the treatment of disease

Assignee: CANOPY GROWTH CORPPriority: Sep 26, 2007Filed: Dec 17, 2019Published: May 21, 2020
Est. expirySep 26, 2027(~1.1 yrs left)· nominal 20-yr term from priority
A61P 17/04A61Q 19/00A61P 1/04A61K 8/9789A61P 17/00A61Q 19/008A61P 1/00A61P 11/02A61P 17/10A61P 39/00A61P 17/06A61K 2121/00A61P 37/08A61P 29/00A61P 11/06A61K 8/97A61K 36/185A61K 36/3482
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Claims

Abstract

The present invention relates to a plant extract from a low-tetrahydrocannabinol (THC) variety of Cannabis sativa subsp. sativa for the treatment of disease. The invention further relates to the production of the extract and pharmaceutical compositions comprising said extract and the uses thereof.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . Plant extract from the flowers and/or flower-proximal leaves and/or stalks and/or roots and/or seeds of a low-tetrahydrocannabinol (THC) variety of  Cannabis sativa  subspecies  sativa  for the treatment of diseases. 
     
     
         2 . Plant extract according to  claim 1 , wherein solvents and/or mixtures of solvents are used as the extraction medium, the solvents being selected from the group comprising water, table salt solution, low-molecular-weight alcohols, acetone, esters, and ethers. 
     
     
         3 . Plant extract according to  claim 2 , wherein, 0.9% table salt solution, 90% ethanol, or 70% isopropanol is used as the extraction medium. 
     
     
         4 . Plant extract according to  claim 1 , wherein the low-THC variety of  Cannabis sativa  subspecies  sativa  is the variety Futura 75. 
     
     
         5 . Plant extract according to  claim 1 , wherein the THC content is less than 2% (wt.-%) THC content. 
     
     
         6 . Method for the production of a plant extract from the flowers and/or flower-proximal leaves and/or stalks and/or roots and/or seeds of a low-tetrahydrocannabinol (THC) variety of  Cannabis sativa  subspecies  sativa , comprising the steps of
 a) drying the flowers and/or flower-proximal leaves and/or stalks and/or roots and/or seeds,   b) pulverizing the flowers and/or flower-proximal leaves and/or stalks and/or roots and/or seeds, and   c) extracting the flowers and/or flower-proximal leaves and/or stalks and/or roots and/or seeds.   
     
     
         7 . Method according to  claim 6 , wherein the extraction in c) comprises the steps of
 c-1) admixing the flowers and/or flower-proximal leaves and/or stalks and/or roots and/or seeds for 24 hours-48 hours with an extraction medium at room temperature, and   c-2) filtering the extract.   
     
     
         8 . Method according to  claim 6 , further comprising the step of
 d) freeze-drying of the acquired extract or   e) vacuum extraction of the acquired extract.   
     
     
         9 . Method according to  claim 6 , wherein solvents and/or mixtures of solvents are used as the extraction medium, the solvents being selected from the group comprising water, table salt solution, low-molecular-weight alcohols, acetone, esters, and ethers. 
     
     
         10 . Method according to  claim 9 , wherein 0.9% table salt solution, 90% ethanol, or 70% isopropanol is used as the extraction medium. 
     
     
         11 . Method according to  claim 6 , wherein the low-THC variety of  Cannabis sativa  subspecies  sativa  is preferably the variety Futura 75. 
     
     
         12 . Pharmaceutical, cosmetic or dermatological composition, comprising a plant extract made of the flowers and/or flower-proximal leaves and/or stalks and/or roots and/or seeds of one and/or multiple low-THC varieties of  Cannabis sativa  subspecies  sativa , produced according to the method of  claim 6 , and further pharmaceutically suitable aids and/or additives. 
     
     
         13 . (canceled) 
     
     
         14 . (canceled) 
     
     
         15 . (canceled) 
     
     
         16 . (canceled) 
     
     
         17 . Plant extract according to  claim 1 , wherein the THC content is less than 0.5 to 0.2% or as low as 0.1 or 0% (wt.-%) THC content

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