US2020170627A1PendingUtilityA1

Sampling systems and related materials and methods

63
Assignee: PROGENITY INCPriority: Aug 18, 2016Filed: Feb 11, 2020Published: Jun 4, 2020
Est. expiryAug 18, 2036(~10.1 yrs left)· nominal 20-yr term from priority
B01L 3/50B01L 3/5023A61B 10/0045G01N 33/56938A61B 5/42G01N 1/405G01N 33/56944G01N 33/56916B01L 3/5085B01L 2200/0621A61B 10/02B01L 2300/087B01L 2400/0677A61B 2010/0061B01L 2300/0636B01L 2400/0633B01L 2300/0832B01L 2400/0475B01L 2200/0689A61B 10/0038B01L 2300/088B01L 2300/069A61B 2562/162B01L 2400/0472B01L 2200/141A61B 5/14539B01L 2300/042B01L 2300/1883A61B 5/0071B01L 2300/12B01L 2300/0877
63
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Claims

Abstract

Sampling systems that include an absorbent material a preservative, such as an analyte preservative, as well as related materials and methods, are disclosed.

Claims

exact text as granted — not AI-modified
1 - 186 . (canceled) 
     
     
         187 . An ingestible device, comprising:
 a housing;   a chamber inside the housing; and   at least five different enzyme inhibitors inside the chamber.   
     
     
         188 . The ingestible device of  claim 187 , wherein the at least five different enzyme inhibitors comprise at least one protease inhibitor. 
     
     
         189 . The ingestible device of  claim 187 , wherein the at least five different enzyme inhibitors comprise at least two different protease inhibitors. 
     
     
         190 . The ingestible device of  claim 187 , wherein the at least five different enzyme inhibitors comprise at least three different protease inhibitors. 
     
     
         191 . The ingestible device of  claim 187 , wherein the at least five different enzyme inhibitors comprise at least four different protease inhibitors. 
     
     
         192 . The ingestible device of  claim 187 , wherein the at least five different enzyme inhibitors comprise at least one serine protease inhibitor. 
     
     
         193 . The ingestible device of  claim 187 , wherein the at least five different enzyme inhibitors comprise at least two different serine protease inhibitors. 
     
     
         194 . The ingestible device of  claim 187 , wherein the at least five different enzyme inhibitors comprise at least three different serine protease inhibitors. 
     
     
         195 . The ingestible device of  claim 187 , wherein the at least five different enzyme inhibitors comprise at least one metalloproteinase inhibitor. 
     
     
         196 . The ingestible device of  claim 187 , wherein the at least five different enzyme inhibitors comprise at least one aspartyl protease inhibitor. 
     
     
         197 . The ingestible device of  claim 187 , further comprising at least one stabilizer. 
     
     
         198 . The ingestible device of  claim 187 , further comprising a member having first and second positions, wherein:
 when the member is in its first position, the member covers an opening in the housing to prevent fluid communication between an exterior of the housing and the chamber via the opening; and   when the member is in its second position, the member does not prevent fluid communication between an exterior of the housing and the chamber via the opening.   
     
     
         199 . An ingestible device, comprising:
 a housing;   a chamber inside the housing; and   at least three different serine protease inhibitors inside the chamber.   
     
     
         200 . The ingestible device of  claim 198 , further comprising at least one metalloproteinase inhibitor. 
     
     
         201 . The ingestible device of  claim 199 , further comprising at least one aspartyl protease inhibitor. 
     
     
         202 . The ingestible device of  claim 200 , further comprising at least one stabilizer. 
     
     
         203 . The ingestible device of  claim 198 , further comprising at least one aspartyl protease inhibitor. 
     
     
         204 . The ingestible device of  claim 203 , further comprising at least one stabilizer. 
     
     
         205 . The ingestible device of  claim 198 , further comprising at least one stabilizer. 
     
     
         206 . The ingestible device of  claim 198 , further comprising a member having first and second positions, wherein:
 when the member is in its first position, the member covers an opening in the housing to prevent fluid communication between an exterior of the housing and the chamber via the opening; and   when the member is in its second position, the member does not prevent fluid communication between an exterior of the housing and the chamber via the opening.   
     
     
         207 . An ingestible device, comprising:
 a housing;   a chamber inside the housing;   a serine protease inhibitor inside the chamber;   an aspartyl protease inhibitor inside the chamber; and   a metalloproteinase inhibitor inside the chamber.   
     
     
         208 . The ingestible device of  claim 207 , further comprising a member having first and second positions, wherein:
 when the member is in its first position, the member covers an opening in the housing to prevent fluid communication between an exterior of the housing and the chamber via the opening; and   when the member is in its second position, the member does not prevent fluid communication between an exterior of the housing and the chamber via the opening.

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