Bile acid synthesis promoter, composition for promoting bile acid synthesis and food composition for promoting bile acid synthesis

Abstract

[Problem] To provide a novel medicine that is capable of promoting cholesterol metabolism to thereby treat, ameliorate or prevent various symptoms associated with increase in blood cholesterol level. [Solution] The present inventors newly found that arctigenin has an effect of promoting the conversion of cholesterol into bile acid. The present invention provides a bile acid synthesis promoter, a composition for promoting bile acid synthesis and a food composition for promoting bile acid synthesis each comprising arctigenin and/or arctiin as active ingredient(s).

1 . A bile acid synthesis promoter comprising arctigenin and/or arctiin as an active ingredient(s). 
     
     
         2 . A composition for promoting bile acid synthesis comprising arctigenin and/or arctiin as an active ingredient(s). 
     
     
         3 . A composition for promoting bile acid synthesis according to  claim 2  comprising said arctigenin and/or arctiin as burdock, burdock fruit, burdock sprout or  Forsythia  fruit or extracts thereof. 
     
     
         4 . A food composition for promoting bile acid synthesis comprising arctigenin and/or arctiin as an active ingredient(s). 
     
     
         5 . A food composition for promoting bile acid synthesis according to  claim 4  comprising said arctigenin and/or arctiin as burdock, burdock fruit, burdock sprout or  Forsythia  fruit or extracts thereof. 
     
     
         6 . An expression promoter of bile acid synthetic enzymes comprising arctigenin and/or arctiin as an active ingredient(s). 
     
     
         7 . A bile acid excretion promoter comprising arctigenin and/or arctiin as an active ingredient(s). 
     
     
         8 . A cholesterol metabolism promoter in the liver comprising arctigenin and/or arctiin as active ingredient(s).