Cell processing system and cell processing device

Abstract

A cell processing system comprising an enclosure 601, an outer enclosure 701 that envelops the enclosure 601, an intake air purification filter 602 provided in the enclosure 601, that purifies gas that has been drawn in from outside the enclosure 601, a circulating apparatus, inside the outer enclosure 701, that circulates gas inside and outside the enclosure 601 in such a manner that gas in the outer enclosure 701 is drawn into the enclosure 601 through the intake air purification filter 602 and gas inside the enclosure 601 is discharged into the outer enclosure 701, and a cell processing apparatus for processing of cells, disposed inside the enclosure 601.

1 - 116 . (canceled) 
     
     
         117 . A cell processing apparatus comprising:
 a cell processing instrument that processes cells,   an embedding member that embeds the cell processing instrument, and   a communicating solution-feeding channel that allows communication between the outside of the embedding member and the cell processing instrument inside the embedding member,   wherein   the cell processing instrument comprises a mononuclear cell separating unit, disposed inside the embedding member, that separates mononuclear cells from blood,   the cell processing apparatus further comprises a separating agent storing unit, disposed outside the embedding member, that stores a separating agent for separation of mononuclear cells, and   the communicating solution-feeding channel comprises a separating agent solution-feeding channel that allows communication between the separating agent storing unit and the mononuclear cell separating unit.   
     
     
         118 . A cell processing apparatus comprising:
 a cell processing instrument that processes cells,   an embedding member that embeds the cell processing instrument, and   a communicating solution-feeding channel that allows communication between the outside of the embedding member and the cell processing instrument inside the embedding member,   wherein the cell processing instrument comprises:   a mononuclear cell separating unit, disposed inside the embedding member,   
       that separates mononuclear cells from blood,
 a factor introducing device, disposed inside the embedding member, that introduces an inducing factor into cells to prepare inducing factor-introduced cells, and 
 a preintroduction cell solution-feeding channel, disposed inside the embedding member, that allows communication between the mononuclear cell separating unit and the factor introducing device. 
 
     
     
         119 . A cell processing apparatus comprising:
 a cell processing instrument that processes cells,   an embedding member that embeds the cell processing instrument, and   a communicating solution-feeding channel that allows communication between the outside of the embedding member and the cell processing instrument inside the embedding member,   wherein the cell processing instrument comprises:   a mononuclear cell purifying filter, disposed inside the embedding member,   a factor introducing device, disposed inside the embedding member, that introduces an inducing factor into cells to prepare inducing factor-introduced cells, and   a preintroduction cell solution-feeding channel, disposed inside the embedding member, that allows communication between the mononuclear cell purifying filter and the factor introducing device.   
     
     
         120 . A cell processing apparatus comprising:
 a cell processing instrument that processes cells,   an embedding member that embeds the cell processing instrument, and   a communicating solution-feeding channel that allows communication between the outside of the embedding member and the cell processing instrument inside the embedding member,   wherein   the cell processing instrument comprises an initializing culturing vessel, disposed inside the embedding member, that cultures inducing factor-introduced cells into which an inducing factor has been introduced,   the cell processing apparatus further comprises a blood cell culture medium storing unit, disposed outside the embedding member, that stores blood cell culture medium, and   the communicating solution-feeding channel comprises a culture medium solution-feeding channel that allows communication between the blood cell culture medium storing unit and the initializing culturing vessel.   
     
     
         121 . The cell processing apparatus according to  claim 120 , wherein the blood cell culture medium is supplied to the initializing culturing vessel at a prescribed timing. 
     
     
         122 . A cell processing apparatus comprising:
 a cell processing instrument that processes cells,   an embedding member that embeds the cell processing instrument, and   a communicating solution-feeding channel that allows communication between the outside of the embedding member and the cell processing instrument inside the embedding member,   wherein   the cell processing instrument comprises an initializing culturing vessel, disposed inside the embedding member, that cultures inducing factor-introduced cells into which an inducing factor has been introduced,   the cell processing apparatus further comprises a stem cell culture medium storing unit, disposed outside the embedding member, that stores stem cell culture medium, and   the communicating solution-feeding channel comprises a culture medium solution-feeding channel that allows communication between the stem cell culture medium storing unit and the initializing culturing vessel.   
     
     
         123 . The cell processing apparatus according to  claim 122 , wherein the stem cell culture medium is supplied to the initializing culturing vessel at a prescribed timing. 
     
     
         124 . A cell processing apparatus comprising:
 a cell processing instrument that processes cells,   an embedding member that embeds the cell processing instrument, and   a communicating solution-feeding channel that allows communication between the outside of the embedding member and the cell processing instrument inside the embedding member,   wherein   the cell processing instrument comprises an initializing culturing vessel, disposed inside the embedding member, that cultures inducing factor-introduced cells into which an inducing factor has been introduced,   the cell processing apparatus further comprises a waste liquid storage section, disposed outside the embedding member, that stores waste liquid, and   the communicating solution-feeding channel comprises a waste liquid solution-feeding channel that allows communication between the initializing culturing vessel and the waste liquid storage section.   
     
     
         125 . A cell processing apparatus comprising:
 a cell processing instrument that processes cells,   an embedding member that embeds the cell processing instrument, and   a communicating solution-feeding channel that allows communication between the outside of the embedding member and the cell processing instrument inside the embedding member,   wherein   the cell processing instrument comprises an initializing culturing vessel, disposed inside the embedding member, that cultures inducing factor-introduced cells into which an inducing factor has been introduced, and   the initializing culturing vessel comprises:   a suspension culture vessel, which comprises:   a dialysis tube in which the inducing factor-introduced cells and culture medium are to be accommodated, and   a vessel in which the dialysis tube is to be placed, with the culture medium accommodable around the periphery of the dialysis tube.   
     
     
         126 . A cell processing apparatus comprising:
 a cell processing instrument that processes cells,   an embedding member that embeds the cell processing instrument, and   a communicating solution-feeding channel that allows communication between the outside of the embedding member and the cell processing instrument inside the embedding member,   wherein the cell processing instrument comprises:   a factor introducing device, disposed inside the embedding member, that introduces an inducing factor into cells to prepare inducing factor-introduced cells,   an initializing culturing vessel, disposed inside the embedding member, that cultures the inducing factor-introduced cells, and   an introduced cell solution-feeding channel, disposed inside the embedding member, that allows communication between the factor introducing device and the initializing culturing vessel.   
     
     
         127 . The cell processing apparatus according to  claim 126 , which further comprises a driving unit disposed outside the embedding member, for feeding of a solution in the introduced cell solution-feeding channel. 
     
     
         128 . The cell processing apparatus according to  claim 127 , wherein the driving unit is connected to an outer wall of the embedding member. 
     
     
         129 . The cell processing apparatus according to  claim 127 , which is provided with a slave unit in the embedding member, to which driving force from the driving unit is transmitted, with the slave unit being connected to the introduced cell solution-feeding channel. 
     
     
         130 . The cell processing apparatus according to  claim 129 , wherein the driving unit and the slave unit are connected by magnetic force. 
     
     
         131 . A cell processing apparatus comprising:
 a cell processing instrument that processes cells,   an embedding member that embeds the cell processing instrument, and   a communicating solution-feeding channel that allows communication between the outside of the embedding member and the cell processing instrument inside the embedding member,   wherein   the cell processing instrument comprises an amplifying culturing vessel, disposed inside the embedding member, that carries out amplifying culturing of a plurality of cell masses comprising established stem cells,   the cell processing apparatus further comprises a stem cell culture medium storing unit, disposed outside the embedding member, that stores stem cell culture medium, and   the communicating solution-feeding channel comprises a culture medium solution-feeding channel that allows communication between the stem cell culture medium storing unit and the amplifying culturing vessel.   
     
     
         132 . The cell processing apparatus according to  claim 131 , wherein the stem cell culture medium is supplied to the amplifying culturing vessel at a prescribed timing. 
     
     
         133 . A cell processing apparatus comprising:
 a cell processing instrument that processes cells,   an embedding member that embeds the cell processing instrument, and   a communicating solution-feeding channel that allows communication between the outside of the embedding member and the cell processing instrument inside the embedding member,   wherein the cell processing instrument comprises:   an initializing culturing vessel, disposed inside the embedding member, that cultures cells,   an amplifying culturing vessel, disposed inside the embedding member, that carries out amplifying culturing of a plurality of cell masses comprising established stem cells, and   an introduced cell solution-feeding channel, disposed inside the embedding member, that allows communication between the initializing culturing vessel and the amplifying culturing vessel.   
     
     
         134 . The cell processing apparatus according to  claim 133 , which further comprises a driving unit disposed outside the embedding member, for feeding of a solution in the introduced cell solution-feeding channel. 
     
     
         135 . The cell processing apparatus according to  claim 134 , wherein the driving unit is connected to an outer wall of the embedding member. 
     
     
         136 . The cell processing apparatus according to  claim 134 , which is provided with a slave unit in the embedding member, to which driving force from the driving unit is transmitted, with the slave unit being connected to the introduced cell solution-feeding channel. 
     
     
         137 . The cell processing apparatus according to  claim 133 , wherein the cell processing instrument further comprises a cell dissociater, disposed inside the embedding member and provided to the introduced cell solution-feeding channel, for dissociation of the cell masses. 
     
     
         138 . A cell processing apparatus comprising:
 a cell processing instrument that processes cells,   an embedding member that embeds the cell processing instrument, and   a communicating solution-feeding channel that allows communication between the outside of the embedding member and the cell processing instrument inside the embedding member,   wherein the cell processing instrument comprises:   an amplifying culturing vessel, disposed inside the embedding member, that carries out amplifying culturing of a plurality of cell masses comprising established stem cells,   a solution exchanger that exchanges a solution surrounding cells, and   an introduced cell solution-feeding channel, disposed inside the embedding member, that allows communication between the amplifying culturing vessel and the solution exchanger.   
     
     
         139 . A cell processing apparatus comprising:
 a cell processing instrument that processes cells,   an embedding member that embeds the cell processing instrument, and   a communicating solution-feeding channel that allows communication between the outside of the embedding member and the cell processing instrument inside the embedding member,   wherein the cell processing instrument comprises a cell mass dissociater that dissociates cell masses.   
     
     
         140 . The cell processing apparatus according to  claim 117 , which further comprises a driving unit disposed outside the embedding member, for feeding of a solution in the communicating solution-feeding channel. 
     
     
         141 . The cell processing apparatus according to  claim 140 , wherein the driving unit is connected to an outer wall of the embedding member. 
     
     
         142 . The cell processing apparatus according to  claim 140 , which is provided with a slave unit in the embedding member, to which driving force from the driving unit is transmitted, with the slave unit being connected to the communicating solution-feeding channel. 
     
     
         143 . A cell processing apparatus comprising:
 a cell processing instrument that processes cells,   an embedding member that embeds the cell processing instrument, and   a communicating solution-feeding channel that allows communication between the outside of the embedding member and the cell processing instrument inside the embedding member, and   a tubing pump, disposed inside the embedding member, for feeding of a solution in the communicating solution-feeding channel,   wherein the cells are cultured by the cell processing instrument.