Systems, devices and methods for analyte monitoring system

Abstract

Systems and methods are provided for detecting changes or fluctuations in an analyte concentration signal that are abnormal, e.g., exceed a predetermined threshold, current trend of analyte concentration measurements, etc. Signals indicative of an analyte concentration in a host may be received from an analyte sensor. The signals may be monitored, and a determination can be made as to whether there is a change in the signal. Upon detecting such a change, the change can be compensated for such that a representation of the signal indicates the analyte concentration. Optionally, the cause of the detected changes or fluctuations can also be determined and information regarding the detected changes or fluctuations can be recorded and analyzed for subsequent optimization of the systems and methods as well for transmitting alerts, notifications, etc. to a user to take corrective action.

1 - 20 . (canceled) 
     
     
         21 . A sensor system comprising:
 a first sensor configured to generate a first signal related to an analyte concentration in a host;   a second sensor configured to generate a second signal related to an orientation of the host;   sensor electronics operably connected to the first sensor and the second sensor, wherein the sensor electronics is configured to generate first data from the first signal and second data from the second signal;   a processor configured to detect a correlation between the first data and the second data.   
     
     
         22 . The sensor system of  claim 21 , wherein the processor is configured to detect an orientation that causes host tissue compression. 
     
     
         23 . The sensor system of  claim 21 , wherein the processor is configured to correlate an orientation with a fluctuation in the first signal. 
     
     
         24 . The sensor system of  claim 23 , wherein the processor is configured to detect a decrease in the first signal caused by lack of oxygen at the first sensor. 
     
     
         25 . The sensor system of  claim 22 , wherein the processor is configured to detect a fluctuation in the first signal caused by the host tissue compression. 
     
     
         26 . The sensor system of  claim 21 , wherein the second data indicates that the host is laying on at least a portion of the analyte sensor system. 
     
     
         27 . The sensor system of  claim 21 , wherein the first sensor comprises a transcutaneous glucose sensor. 
     
     
         28 . The sensor system of  claim 21 , wherein the second sensor comprises an accelerometer. 
     
     
         29 . The sensor system of  claim 27 , wherein the second sensor comprises an accelerometer. 
     
     
         30 . The sensor system of  claim 28 , wherein the accelerometer comprises a three-axis accelerometer. 
     
     
         31 . The sensor system of  claim 21 , wherein the processor is configured to detect an inverted orientation. 
     
     
         32 . The sensor system of  claim 28 , wherein the analyte sensor system additionally comprises a three-axis compass. 
     
     
         33 . The sensor system of  claim 21 , further comprising a real-time clock. 
     
     
         34 . The sensor system of  claim 33 , wherein the processor is configured to utilize a time of day in combination with the second signal to correlate a fluctuation in the first signal to the orientation 
     
     
         35 . The sensor system of  claim 23 , wherein the processor is configured to detect a fluctuation in the first signal that follows a pattern uncharacteristic of physiological changes to the analyte concentration within the host. 
     
     
         36 . The sensor system of  claim 21 , wherein the sensor electronics comprises the processor. 
     
     
         37 . The sensor system of  claim 21 , further comprising a display device in wireless communication with the sensor electronics. 
     
     
         38 . The sensor system of  claim 37 , wherein the processor is part of the display device or the sensor electronics. 
     
     
         39 . The sensor system of  claim 37 , wherein the display device is configured to provide alerts to the host. 
     
     
         40 . The sensor system of  claim 39 , wherein the alert comprises an instruction for the host to change position. 
     
     
         41 . A method for measuring an analyte concentration of a host, the method comprising:
 generating a first signal from a transcutaneous analyte sensor, wherein the first signal is related to an analyte concentration in the host;   generating a second signal from another sensor, wherein the second signal is related to an orientation of the host;   receiving, by sensor electronics of the analyte sensor system, the first signal and the second signal; and   correlating characteristics of the first signal with characteristics of the second signal.   
     
     
         42 . The method of  claim 41 , comprising generating the second signal from an accelerometer. 
     
     
         43 . The method of  claim 42 , comprising detecting an inverted orientation of the accelerometer. 
     
     
         44 . The method of  claim 41 , comprising detecting the host laying on at least a portion of the analyte sensor system. 
     
     
         45 . The method of  claim 44 , comprising providing a notification to the host instructing the host to change position. 
     
     
         46 . An analyte sensing system comprising:
 a transcutaneous analyte sensor;   an accelerometer;   sensor electronics operably coupled to the transcutaneous analyte sensor and the accelerometer to receive a transcutaneous analyte sensor signal and an accelerometer signal therefrom;   a processor configured to determine an orientation of the accelerometer from the accelerometer signal; and   wherein the processor is configured to correlate characteristics of the transcutaneous analyte sensor signal with the determined orientation of the accelerometer.   
     
     
         47 . The analyte sensing system of  claim 46 , further comprising a display device. 
     
     
         48 . The analyte sensing system of  claim 47 , wherein the display device comprises the processor. 
     
     
         49 . The analyte sensing system of  claim 46 , wherein the sensor electronics comprises the processor. 
     
     
         50 . The analyte sensor system of  claim 46 , further comprising a real time clock. 
     
     
         51 . The analyte sensor system of  claim 46 , wherein the accelerometer is a three-axis accelerometer. 
     
     
         52 . The analyte sensor system of  claim 46 , wherein the processor is configured to detect an inverted orientation of the accelerometer.