Method for identifying of a biological sample of a mammal, composition for use in this method and kit for performance of this method

Abstract

The invention relates to methods through which a biological sample of a mammal can be precisely assigned and identified, comprising administering at least one essentially non-metabolizable marker substance and a dye.

1 . A method for identifying a biological sample of a mammal comprising:
 administration of a composition comprising an essentially non-metabolizable marker substance and a dye to the mammal;   drawing of a biological sample from the mammal; and   examination of the biological sample for the presence and/or amount of the essentially non-metabolizable marker substance and optionally of the dye.   
     
     
         2 . The method of  claim 1 , wherein the mammal is selected from the group consisting of humans, cattle, pigs, sheep and horses. 
     
     
         3 . The method of  claim 1 , wherein the identified biological sample is examined for at least one specified analyte. 
     
     
         4 . The method of  claim 1 , wherein the capsule contains a computer-readable code. 
     
     
         5 . A method for identifying a biological sample of a mammal comprising:
 administering a capsule composition comprising an essentially non-metabolizable marker substance and a dye to the mammal;   collecting a biological sample from the mammal; and   submitting the biological sample for examination for the presence and/or amount of the essentially non-metabolizable marker substance and optionally of the dye.   
     
     
         6 . The method of  claim 5 , in which the dye is chosen from the group consisting of Allura Red AC (E 129), aluminum (E 173), amaranth (E 123), anthocyanins (E 163), azorubin (E 122), betanin (E 162), brown FK (E 154), brown HT (E 155), brilliant blue FCF (E 133), brilliant black BN (E 151), calcium carbonate (E 170), canthaxanthine (E 161 g), carotene (E 160 a), annatto (N orbixin) (E 160 b), capsanthin (E 160 c), lycopene (E 160 d), 8′-apo-β-ca rotenal-81-al (E 160 e), ethyl-8′apo-β-carotenal-8′oate (E 160 f), quinoline yellow (E 104), chlorophyll (E 140), cochenille red A (E 124), curcumin (E 100), iron oxide (E 172), erythrosine (E 127), yellow orangeS (E 110), gold (E175), greenS (E 142), indigotine (E 132), cochineal (E 120), copper-containing complexes of chlorophylls and chlorophyllines (E 141), lactoflavin (E 101), litholrubin BK (E 180), lutein (E 161 b), patent blue V (E 131), vegetable charcoals (E 153), riboflavin (vitamin B2) (E 101), riboflavin-5-phosphate (E 101 a), safflower, silver (E 174), tartrazine (E 102), titanium dioxide (E 171), caramel color (E 150 a), caustic sulfite-caramel color (E 150 b), ammonia-caramel color (E 150 c), ammonium sulfite-caramel color (E 150 d) and zeaxanthin (E 161 h). 
     
     
         7 . The method of  claim 5  further comprising at least one additional marker substance. 
     
     
         8 . The method of  claim 7 , wherein the at least one additional marker substance is metabolizable. 
     
     
         9 . The method of  claim 5 , wherein the capsule composition comprises two essentially non-metabolizable marker substances with different molecular weights. 
     
     
         10 . The method of  claim 9 , wherein the two essentially non-metabolizable marker substances are two polyethylene glycols with different molecular weights of less than 5000 Da, present in an amount sufficient for detection in a biological sample from a mammal upon ingestion of the capsule by the mammal. 
     
     
         11 . The method of  claim 5 , wherein the capsule contains a computer-readable code. 
     
     
         12 . The method of  claim 5 , wherein the biological sample is urine. 
     
     
         13 . The method of  claim 5 , wherein the dye is present in an amount sufficient to color a body part of a first mammal if the first mammal attempts to transfer the non-metabolizable marker to a biological sample from of second mammal. 
     
     
         14 . The method of  claim 13 , wherein the body part is the oral mucosa. 
     
     
         15 . The method of  claim 14 , wherein the capsule composition is configured such that the dye does not color the oral mucosa of a mammal upon oral administration of the capsule to the mammal. 
     
     
         16 . The method of  claim 5 , wherein the dye is in solution. 
     
     
         17 . The method of  claim 5 , wherein the marker substance serves as solvent for the dye. 
     
     
         18 . The method of  claim 10 , wherein the at least two polyethylene glycols each have different molecular weight of less than 4000 Da. 
     
     
         19 . The method of  claim 5 , wherein the capsule composition does not contain riboflavin. 
     
     
         20 . The method of  claim 5 , wherein the capsule composition is part of a kit.