US2020323852A1PendingUtilityA1

Compounds And Compositions As Protein Kinase Inhibitors

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Assignee: ARRAY BIOPHARMA INCPriority: Aug 28, 2009Filed: Jan 14, 2020Published: Oct 15, 2020
Est. expiryAug 28, 2029(~3.1 yrs left)· nominal 20-yr term from priority
Inventors:Shenlin HuangXianming JinZuosheng LiuDaniel PoonJohn TellewYongqin WanXing WangYongping Xie
C07D 403/04C07D 401/14A61K 31/506A61K 45/06A61P 35/00A61K 9/0053C07D 405/14A61P 25/24A61P 43/00A61K 31/4184A61P 1/08
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Claims

Abstract

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of B-Raf.

Claims

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1 . A compound which is 
       
         
           
           
               
               
           
         
       
       (S)-methyl 1-(4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-ylamino)propan-2-ylcarbamate.

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